Rabbit DNAJC10 Polyclonal Antibody | anti-DNAJC10 antibody

DNAJC10 Rabbit Polyclonal

Cat. Num. AAA768689

• Gene Names: DNAJC10; JPDI; MTHr; ERdj5; PDIA19
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: DNAJC10; Polyclonal Antibody; DNAJC10 Rabbit Polyclonal; anti-DNAJC10 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 332

• Applicable Applications for anti-DNAJC10 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen: DnaJ (Hsp40) homolog, subfamily C, member 10
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human pancreas cancer using MBS768689 (DNAJC10 antibody) at dilution of 1:100)

Western Blot (WB)

(HeLa cells were subjected to SDS PAGE followed by western blot with MBS768689 (DNAJC10 antibody) at dilution of 1:1500)

NCBI and Uniprot Product Information

• NCBI GI #: 78174373
• NCBI GeneID: 54431
• Molecular Weight: 37,682 Da
• NCBI Official Full Name: DNAJC10 protein
• NCBI Official Synonym Full Names: DnaJ heat shock protein family (Hsp40) member C10
• NCBI Official Symbol: DNAJC10
• NCBI Official Synonym Symbols: JPDI; MTHr; ERdj5; PDIA19
• NCBI Protein Information: dnaJ homolog subfamily C member 10
• UniProt Protein Name: DnaJ homolog subfamily C member 10
• Protein Family: DnaJ homolog subfamily
• UniProt Gene Name: DNAJC10
• UniProt Synonym Gene Names: ERDJ5; ER-resident protein ERdj5; ERdj5; MTHr
• UniProt Entry Name: DJC10_HUMAN

NCBI Description

This gene encodes an endoplasmic reticulum co-chaperone which is part of the endoplasmic reticulum-associated degradation complex involved in recognizing and degrading misfolded proteins. The encoded protein reduces incorrect disulfide bonds in misfolded glycoproteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012]

Uniprot Description

DNAJC10: This endoplasmic reticulum co-chaperone may play a role in protein folding and translocation across the endoplasmic reticulum membrane. May act as a co-chaperone for HSPA5. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted; Endoplasmic reticulum; Chaperone

Chromosomal Location of Human Ortholog: 2q32.1

Cellular Component: endoplasmic reticulum; endoplasmic reticulum lumen; membrane

Molecular Function: ATPase activator activity; ATPase binding; chaperone binding; disulfide oxidoreductase activity; Hsp70 protein binding; misfolded protein binding; oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor; protein binding; protein disulfide oxidoreductase activity

Biological Process: cell redox homeostasis; ER-associated protein catabolic process; negative regulation of protein amino acid phosphorylation; positive regulation of ATPase activity