Rabbit anti-Human DNAJB2 Polyclonal Antibody | anti-DNAJB2 antibody

DNAJB2 Antibody

Cat. Num. AAA7045045

• Gene Names: DNAJB2; HSJ1; CMT2T; DSMA5; HSJ-1; HSPF3
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Antigen Affinity Purified
• Synonyms: DNAJB2; Polyclonal Antibody; DNAJB2 Antibody; DnaJ homolog subfamily B member 2; DnaJ protein homolog 1; Heat shock 40 kDa protein 3; Heat shock protein J1; HSJ-1; HSJ1; HSPF3; anti-DNAJB2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 277

• Applicable Applications for anti-DNAJB2 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Species: Human
• Immunogen: Recombinant human DnaJ homolog subfamily B member 2 protein (C-110AA)
• Conjugate: Non-conjugated
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-109472
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: DNAJB2 antibody at 1.18ug/mlLane 1: 293T whole cell lysateLane 2: PC-3 whole cell lysateLane 3: A431 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 36,31 kDaObserved band size: 36 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human brain tissue MBS7045045 at dilution 1:100)

Related Product Information for anti-DNAJB2 antibody

cytosol, inclusion body, nucleus, chaperone binding, Hsp70 protein binding, polyubiquitin binding, proteasome binding, ubiquitin protein ligase binding, unfolded protein binding, ER-associated ubiquitin-dependent protein catabolic process

NCBI and Uniprot Product Information

• NCBI GI #: 88501736
• NCBI GeneID: 3300
• NCBI Accession #: NP_001034639.1
• NCBI GenBank Nucleotide #: NM_001039550.1
• UniProt Accession #: P25686; Q8IUK1; Q8IUK2; Q96F52; A8K9P6
• Molecular Weight: 30,569 Da
• NCBI Official Full Name: dnaJ homolog subfamily B member 2 isoform a
• NCBI Official Synonym Full Names: DnaJ heat shock protein family (Hsp40) member B2
• NCBI Official Symbol: DNAJB2
• NCBI Official Synonym Symbols: HSJ1; CMT2T; DSMA5; HSJ-1; HSPF3
• NCBI Protein Information: dnaJ homolog subfamily B member 2
• UniProt Protein Name: DnaJ homolog subfamily B member 2
• Protein Family: DnaJ homolog subfamily
• UniProt Gene Name: DNAJB2
• UniProt Synonym Gene Names: HSJ1; HSPF3; HSJ-1
• UniProt Entry Name: DNJB2_HUMAN

NCBI Description

This gene is almost exclusively expressed in the brain, mainly in the neuronal layers. It encodes a protein that shows sequence similarity to bacterial DnaJ protein and the yeast homologs. In bacteria, this protein is implicated in protein folding and protein complex dissociation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011]

Uniprot Description

DNAJB2: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: cytosol; nucleus

Molecular Function: chaperone binding; unfolded protein binding

Biological Process: protein folding; protein refolding; response to unfolded protein

Disease: Charcot-marie-tooth Disease, Axonal, Type 2t; Spinal Muscular Atrophy, Distal, Autosomal Recessive, 5