Goat DNAH8 Polyclonal Antibody | anti-DNAH8 antibody
Goat anti-DNAH8 (aa107 -117) Antibody
Western Blot: Not yet tested - our routinely used western blotting protocol does not allow detection of proteins as large as the calculated size of 515kDa according to NP_001362.2. Therefore we cannot recommend an optimal concentration and the antibody is an aspiring product.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a heavy chain of an axonemal dynein involved in sperm and respiratory cilia motility. Axonemal dyneins generate force through hydrolysis of ATP and binding to microtubules. [provided by RefSeq, Jan 2012]
Uniprot Description
DNAH8: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly. Belongs to the dynein heavy chain family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Microtubule-binding; Motor
Chromosomal Location of Human Ortholog: 6p21.2
Cellular Component: axonemal dynein complex; cytoplasm; dynein complex; microtubule
Molecular Function: ATP binding; ATPase activity; microtubule motor activity
Biological Process: ciliary or flagellar motility; metabolic process; microtubule-based movement
Research Articles on DNAH8
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Product Notes
The DNAH8 dnah8 (Catalog #AAA422446) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-DNAH8 (aa107 -117) Antibody reacts with Expected from sequence similarity: Human, Dog, Rabbit and may cross-react with other species as described in the data sheet. AAA Biotech's DNAH8 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 16000. Western Blot: Not yet tested - our routinely used western blotting protocol does not allow detection of proteins as large as the calculated size of 515kDa according to NP_001362.2. Therefore we cannot recommend an optimal concentration and the antibody is an aspiring product. Researchers should empirically determine the suitability of the DNAH8 dnah8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: EGTVKLKTID N. It is sometimes possible for the material contained within the vial of "DNAH8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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