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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human breast cancer using MBS1495912 at dilution 1:100)

Rabbit anti-Human DNA replication complex GINS protein PSF2 Polyclonal Antibody | anti-GINS2 antibody

Rabbit anti-human DNA replication complex GINS protein PSF2 polyclonal Antibody(GINS2)

Gene Names
GINS2; PSF2; Pfs2; HSPC037
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Caprylic Acid Ammonium Sulfate Precipitation Purified
Synonyms
DNA replication complex GINS protein PSF2; Polyclonal Antibody; Rabbit anti-human DNA replication complex GINS protein PSF2 polyclonal Antibody(GINS2); GINS complex subunit 2; CGI-122; DC5; HSPC037; PSF2; GINS2; anti-GINS2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Sequence Length
185
Applicable Applications for anti-GINS2 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human DNA replication complex GINS protein PSF2 protein(1-185AA)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-82718 / sc-82717 / sc-98556
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human breast cancer using MBS1495912 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human breast cancer using MBS1495912 at dilution 1:100)
Related Product Information for anti-GINS2 antibody
The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
21,428 Da
NCBI Official Full Name
DNA replication complex GINS protein PSF2
NCBI Official Synonym Full Names
GINS complex subunit 2 (Psf2 homolog)
NCBI Official Symbol
GINS2
NCBI Official Synonym Symbols
PSF2; Pfs2; HSPC037
NCBI Protein Information
DNA replication complex GINS protein PSF2
UniProt Protein Name
DNA replication complex GINS protein PSF2
UniProt Gene Name
GINS2
UniProt Synonym Gene Names
PSF2
UniProt Entry Name
PSF2_HUMAN

NCBI Description

The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1 (GINS1; MIM 610608), Psf2, and Psf3 (GINS3; MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM, Mar 2008]

Uniprot Description

PSF2: The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single- stranded DNA. Belongs to the GINS2/PSF2 family.

Protein type: DNA replication

Chromosomal Location of Human Ortholog: 16q24.1

Cellular Component: nucleoplasm

Molecular Function: 3'-5' DNA helicase activity; protein binding

Biological Process: DNA duplex unwinding; DNA strand elongation during DNA replication; double-strand break repair via break-induced replication; mitotic cell cycle

Research Articles on GINS2

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Product Notes

The GINS2 gins2 (Catalog #AAA1495912) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human DNA replication complex GINS protein PSF2 polyclonal Antibody(GINS2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DNA replication complex GINS protein PSF2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the GINS2 gins2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DNA replication complex GINS protein PSF2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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