Rabbit anti-Human, Mouse DMTN Polyclonal Antibody | anti-DMTN antibody
Phospho-DMTN (S403) Antibody
IHC: 1:100-1:300
ELISA: 1:10000
NCBI and Uniprot Product Information
NCBI Description
Dematin, or EPB49, is an actin-bundling protein originally identified in the erythroid membrane skeleton. Its actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase and is restored after dephosphorylation (Rana et al., 1993 [PubMed 8341682]).[supplied by OMIM, Apr 2009]
Uniprot Description
dematin: a probable DNA binding protein, with a Myb-like DNA-binding and ELM2 domain.
Protein type: Tumor suppressor; Actin-binding; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 8p21.1
Cellular Component: cortical cytoskeleton; perinuclear region of cytoplasm; cell projection membrane; cytoplasmic membrane-bound vesicle; plasma membrane; endomembrane system; actin filament; cytosol; actin cytoskeleton
Molecular Function: protein binding; protein self-association; spectrin binding; actin binding; receptor binding
Biological Process: regulation of cell shape; actin filament bundle formation; negative regulation of peptidyl-tyrosine phosphorylation; erythrocyte development; positive regulation of blood coagulation; actin filament capping; regulation of actin cytoskeleton organization and biogenesis; negative regulation of focal adhesion formation; negative regulation of peptidyl-serine phosphorylation; cytoskeleton organization and biogenesis; regulation of filopodium formation; protein complex assembly; actin cytoskeleton organization and biogenesis
Research Articles on DMTN
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Product Notes
The DMTN epb49 (Catalog #AAA7119155) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Phospho-DMTN (S403) Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DMTN can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500-1:2000 IHC: 1:100-1:300 ELISA: 1:10000. Researchers should empirically determine the suitability of the DMTN epb49 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DMTN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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