Western Blot (WB)
(DLX4 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the DLX4 antibody detected the DLX4 protein (arrow).)
Rabbit anti-Human DLX4 Polyclonal Antibody | anti-DLX4 antibody
DLX4 Antibody (Center)
Western Blot (WB)
(DLX4 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the DLX4 antibody detected the DLX4 protein (arrow).)
Western Blot (WB)
(DLX4 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the DLX4 antibody detected the DLX4 protein (arrow).)
Western Blot (WB)
(Western blot analysis of DLX4 (arrow) using rabbit polyclonal DLX4 Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DLX4 gene.)
Western Blot (WB)
(Western blot analysis of DLX4 (arrow) using rabbit polyclonal DLX4 Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DLX4 gene.)
identified on the basis of their sequence similarity with
Drosophila developmental genes. Members of the Dlx gene family
contain a homeobox that is related to that of Distal-less (Dll), a
gene expressed in the head and limbs of the developing fruit fly.
The Distal-less (Dlx) family of genes comprises at least 6
different members, DLX1-DLX6. The DLX proteins are postulated to
play a role in forebrain and craniofacial development. Three
transcript variants have been described for this gene, however, the
full length nature of one variant has not been described. Studies
of the two splice variants revealed that one encoded isoform
functions as a repressor of the beta-globin gene while the other
isoform lacks that function.
Schwartz, A.M., et al. Mod. Pathol. 22(1):1-6(2009)
Man, Y.G., et al. Cancer Biomark 5(1):9-17(2009)
Cavalli, L.R., et al. Cancer Genet. Cytogenet. 187(1):19-24(2008)
Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)
NCBI and Uniprot Product Information
NCBI Description
Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function. [provided by RefSeq, Jul 2008]
Uniprot Description
DLX4: May play a role in determining the production of hemoglobin S. May act as a repressor. Belongs to the distal-less homeobox family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription factor; DNA-binding
Chromosomal Location of Human Ortholog: 17q21.33
Cellular Component: nucleus
Molecular Function: protein binding; sequence-specific DNA binding; transcription factor activity
Biological Process: regulation of transcription, DNA-dependent; multicellular organismal development; negative regulation of transcription from RNA polymerase II promoter
Research Articles on DLX4
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Product Notes
The DLX4 dlx4 (Catalog #AAA9207172) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 72-100. The DLX4 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DLX4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the DLX4 dlx4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DLX4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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