Western Blot (WB)
(Western blot analysis of DLX2 Antibody (Center) in 293 cell line lysates (35ug/lane). DLX2 (arrow) was detected using the purified Pab.)
Rabbit anti-Human DLX2 Polyclonal Antibody | anti-DLX2 antibody
DLX2 Antibody (Center)
Western Blot (WB)
(Western blot analysis of DLX2 Antibody (Center) in 293 cell line lysates (35ug/lane). DLX2 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of DLX2 Antibody (Center) in 293 cell line lysates (35ug/lane). DLX2 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human brain tissue reacted with DLX2 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human brain tissue reacted with DLX2 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Subcellular location: Nucleus (Potential).
NCBI and Uniprot Product Information
NCBI Description
Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 2. [provided by RefSeq, Jul 2008]
Uniprot Description
DLX2: Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis. Belongs to the distal-less homeobox family.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 2q32
Cellular Component: nucleus
Molecular Function: single-stranded RNA binding; sequence-specific DNA binding; chromatin binding; transcription factor activity
Biological Process: branching morphogenesis of a nerve; olfactory bulb development; hippocampus development; subpallium development; negative regulation of transcription from RNA polymerase II promoter; embryonic cranial skeleton morphogenesis; odontogenesis of dentine-containing teeth; negative regulation of oligodendrocyte differentiation; cerebral cortex GABAergic interneuron fate commitment; cartilage development; regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment; negative regulation of Notch signaling pathway; positive regulation of transcription from RNA polymerase II promoter; brain development; proximal/distal pattern formation
Research Articles on DLX2
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Product Notes
The DLX2 dlx2 (Catalog #AAA9208351) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 194-222. The DLX2 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DLX2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB). WB~~1:1000. Researchers should empirically determine the suitability of the DLX2 dlx2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DLX2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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