Rabbit DLX1 Polyclonal Antibody | anti-DLX1 antibody
DLX1 (Distalless, DII Family Homeodomain Transcription Factor)
Purified by affinity chromatography.
Purified by affinity chromatography.
Dilution: Western Blot: 1:200-1:1000 (ECL)
Immunohistochemistry: 1:200-1:1000
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-{beta} superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]
Uniprot Description
DLX1: Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis and may be involved in the early development of diencephalic subdivisions. Belongs to the distal-less homeobox family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 2q32
Cellular Component: nucleus
Molecular Function: sequence-specific DNA binding; chromatin binding
Biological Process: negative regulation of oligodendrocyte differentiation; cerebral cortex GABAergic interneuron fate commitment; embryonic skeletal development; hippocampus development; regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment; negative regulation of Notch signaling pathway; subpallium development; negative regulation of transcription from RNA polymerase II promoter; negative regulation of neuron apoptosis; proximal/distal pattern formation; odontogenesis of dentine-containing teeth
Research Articles on DLX1
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Product Notes
The DLX1 dlx1 (Catalog #AAA613109) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DLX1 (Distalless, DII Family Homeodomain Transcription Factor) reacts with Human, Mouse, Rodent and may cross-react with other species as described in the data sheet. AAA Biotech's DLX1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in ELISA, Western Blot and Immunohistochemistry. Dilution: Western Blot: 1:200-1:1000 (ECL) Immunohistochemistry: 1:200-1:1000. Researchers should empirically determine the suitability of the DLX1 dlx1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DLX1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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