Western Blot (WB)
(Western blot analysis of DLST expression in SKOV3 (A), Hela (B), mouse kidney (C), rat liver (D) whole cell lysates.)
Rabbit DLST Polyclonal Antibody | anti-DLST antibody
Anti-DLST Antibody
Western Blot (WB)
(Western blot analysis of DLST expression in SKOV3 (A), Hela (B), mouse kidney (C), rat liver (D) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of DLST expression in SKOV3 (A), Hela (B), mouse kidney (C), rat liver (D) whole cell lysates.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of DLST staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of DLST staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a mitochondrial protein that belongs to the 2-oxoacid dehydrogenase family. This protein is one of the three components (the E2 component) of the 2-oxoglutarate dehydrogenase complex that catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011]
Uniprot Description
DLST: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). Forms a 24-polypeptide structural core with octahedral symmetry. Belongs to the 2-oxoacid dehydrogenase family.
Protein type: Carbohydrate Metabolism - citrate (TCA) cycle; Amino Acid Metabolism - lysine degradation; EC 2.3.1.61; Mitochondrial; Transferase
Chromosomal Location of Human Ortholog: 14q24.3
Cellular Component: membrane; mitochondrial matrix; myelin sheath; nucleus; oxoglutarate dehydrogenase complex; plasma membrane
Molecular Function: chaperone binding; dihydrolipoyllysine-residue succinyltransferase activity; heat shock protein binding
Biological Process: 2-oxoglutarate metabolic process; generation of precursor metabolites and energy; glyoxylate metabolic process; L-lysine catabolic process to acetyl-CoA via saccharopine; lysine catabolic process; NADH metabolic process; tricarboxylic acid cycle
Research Articles on DLST
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Product Notes
The DLST dlst (Catalog #AAA8245137) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-DLST Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DLST can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1/500 - 1/2000; IHC: 1/50 - 1/200. Researchers should empirically determine the suitability of the DLST dlst for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DLST, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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