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Testing Data (Fig-1: Expression analysis of DLL1. Anti-DLL1 antibody (11-10034) was used at 1 ug/ml on h Heart lysate.)

Rabbit DLL1 Polyclonal Antibody | anti-DLL1 antibody

Polyclonal Antibody to DLL1

Gene Names
DLL1; DL1; Delta; DELTA1
Reactivity
Human
Predicted: Mouse
Applications
Western Blot
Purity
Purified
Protein A Chromatography
Synonyms
DLL1; Polyclonal Antibody; Polyclonal Antibody to DLL1; UNQ146/PRO172; Drosophila Delta homolog 1; Antibody to DLL1; Anti-DLL1 Antibody; DLL1 Antibody; anti-DLL1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified
Protein A Chromatography
Form/Format
25 ug in 50 ul/100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Sequence Length
723
Applicable Applications for anti-DLL1 antibody
Western Blot (WB)
Application Notes
WB: 1-2 ug/ml
Immunogen Information
A partial length recombinant DLL1 protein (amino acids 506-714) was used as the immunogen for this antibody.
Antigen
DLL1
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.

Testing Data

(Fig-1: Expression analysis of DLL1. Anti-DLL1 antibody (11-10034) was used at 1 ug/ml on h Heart lysate.)

Testing Data (Fig-1: Expression analysis of DLL1. Anti-DLL1 antibody (11-10034) was used at 1 ug/ml on h Heart lysate.)
Related Product Information for anti-DLL1 antibody
DLL1 (Delta-like 1) is a human homolog of the Drosophila Notch ligand Delta that is the ligand for Notch3. It belongs to the family of Notch ligands and Notch signaling is one of the most conserved pathways in the regulation of cell differentiation and cell fate decisions. DLL1 is expressed in a goblet cell-specific manner in human colonic tissue. DLL1 like notch ligands are known to selectively drive antigen-specific CD4 T helper 1 cell responses which are important in protective immune response in leishmaniasis.
Product Categories/Family for anti-DLL1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
27,355 Da
NCBI Official Full Name
Delta-like protein 1
NCBI Official Synonym Full Names
delta like canonical Notch ligand 1
NCBI Official Symbol
DLL1
NCBI Official Synonym Symbols
DL1; Delta; DELTA1
NCBI Protein Information
delta-like protein 1
UniProt Protein Name
Delta-like protein 1
Protein Family
UniProt Gene Name
DLL1
UniProt Synonym Gene Names
Delta1; H-Delta-1

NCBI Description

DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. [provided by RefSeq, Jul 2008]

Uniprot Description

DLL1: Acts as a ligand for Notch receptors. Blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor. Interacts with Notch receptors. Expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney.

Protein type: Cell development/differentiation; Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 6q27

Cellular Component: adherens junction; apical plasma membrane; lipid raft; plasma membrane

Molecular Function: Notch binding; protein binding; Tat protein binding

Biological Process: astrocyte development; cell differentiation; cerebellar molecular layer formation; cerebellar Purkinje cell layer structural organization; determination of left/right symmetry; heart looping; lateral inhibition; marginal zone B cell differentiation; negative regulation of cell differentiation; negative regulation of cell proliferation; negative regulation of epidermal cell differentiation; negative regulation of epithelial cell differentiation; negative regulation of interleukin-10 production; negative regulation of myoblast differentiation; negative regulation of neuron differentiation; neuron fate specification; Notch receptor processing; Notch signaling pathway; organ growth; positive regulation of cell proliferation; positive regulation of endocytosis; positive regulation of Notch signaling pathway; positive regulation of skeletal muscle growth; positive regulation of transcription from RNA polymerase II promoter; proximal/distal pattern formation; regulation of blood pressure; regulation of cell adhesion; regulation of cell division; regulation of growth; regulation of neurogenesis; regulation of skeletal muscle growth; regulation of somitogenesis; retina development in camera-type eye; retina morphogenesis in camera-type eye; skeletal muscle growth; somitogenesis; spinal cord development

Research Articles on DLL1

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Product Notes

The DLL1 dll1 (Catalog #AAA668627) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to DLL1 reacts with Human Predicted: Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DLL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1-2 ug/ml. Researchers should empirically determine the suitability of the DLL1 dll1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DLL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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