Rabbit anti-Human DIDO1 Polyclonal Antibody | anti-DIDO1 antibody

DIDO1 Antibody

Cat. Num. AAA9400983

• Gene Names: DIDO1; BYE1; DIO1; DATF1; DIDO2; DIDO3; DIO-1; DATF-1; C20orf158; dJ885L7.8
• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Antigen affinity purification.
• Synonyms: DIDO1; Polyclonal Antibody; DIDO1 Antibody; BYE1; DIO1; DATF1; DIDO2; DIDO3; DIO-1; DATF-1; C20orf158; dJ885L7.8; anti-DIDO1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of total DIDO1 protein.
• Purity/Purification: Antigen affinity purification.
• Form/Format: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
• Concentration: 2.6 mg/ml (varies by lot)
• Sequence Length: 2240

• Applicable Applications for anti-DIDO1 antibody: Immunohistochemistry (IHC)
• Application Notes: Immunohistochemistry: 1:50-1:200
• Immunogen Type: Recombinant Protein
• Immunogen Description: Fusion protein corresponding to residues near the C terminal of human death inducer-obliterator 1
• Target Name: DIDO1
• Preparation and Storage: Store at -20 degree C

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/60.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using at dilution 1/60.)

Related Product Information for anti-DIDO1 antibody

Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms.

Product Categories/Family for anti-DIDO1 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 301129170
• NCBI GeneID: 11083
• NCBI Accession #: NP_001180298.1
• NCBI GenBank Nucleotide #: NM_001193369.1
• UniProt Accession #: Q9BTC0; O15043; Q3ZTL7; Q3ZTL8; Q4VXS1; Q4VXS2; Q4VXV8; Q4VXV9; Q96D72; A8MY65; B9EH82; E1P5I1
• Molecular Weight: 61,354 Da
• NCBI Official Full Name: death-inducer obliterator 1 isoform c
• NCBI Official Synonym Full Names: death inducer-obliterator 1
• NCBI Official Symbol: DIDO1
• NCBI Official Synonym Symbols: BYE1; DIO1; DATF1; DIDO2; DIDO3; DIO-1; DATF-1; C20orf158; dJ885L7.8
• NCBI Protein Information: death-inducer obliterator 1
• UniProt Protein Name: Death-inducer obliterator 1
• Protein Family: Death-inducer obliterator
• UniProt Gene Name: DIDO1
• UniProt Synonym Gene Names: C20orf158; DATF1; KIAA0333; DIO-1; hDido1; DATF-1
• UniProt Entry Name: DIDO1_HUMAN

NCBI Description

Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms. [provided by RefSeq, Jul 2008]

Uniprot Description

DATF1: Putative transcription factor, weakly pro-apoptotic when overexpressed. Tumor suppressor. Ubiquitous. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 20q13.33

Cellular Component: cytoplasm; spindle; nucleus

Molecular Function: zinc ion binding

Biological Process: transcription, DNA-dependent