Rabbit DIAP1 Polyclonal Antibody | anti-DIAP1 antibody

Rabbit anti-Drosophila melanogaster (Fruit fly) DIAP1 Polyclonal Antibody

• Gene Names: Diap1; 0736/01; 1065/03; CG12284; D-iap1; D-IAP1; diap; dIAP; Diap; DIAP; diap 1; DIAP I; diap-1; dIAP-1; Diap-1; DIAP-1; Diap-1/Th; diap1; dIap1; dIAP1; DIAP1; diap1/thread; DIAPI; DmelCG12284; E(rpr)3-1; IAP; Iap1; IAP1; l(3)72CDe; l(3)72Dc; l(3)j5C8; l(3)S030
• Reactivity: Drosophila melanogaster (Fruit fly)
• Applications: ELISA, Western Blot
• Purity: Protein A/G
• Synonyms: DIAP1; Polyclonal Antibody; Rabbit anti-Drosophila melanogaster (Fruit fly) DIAP1 Polyclonal Antibody; DIAP1 Antibody; Death-associated inhibitor of apoptosis 1; EC 2.3.2.27; Apoptosis 1 inhibitor; E3 ubiquitin-protein ligase th; Inhibitor of apoptosis 1; Protein thread; RING-type E3 ubiquitin transferase Diap1; Diap1 Iap1 th CG12284; anti-DIAP1 antibody

• Host: Rabbit
• Reactivity: Drosophila melanogaster (Fruit fly)
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Protein A/G
• Form/Format: Liquid; Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH7.4

• Applicable Applications for anti-DIAP1 antibody: ELISA (EIA), WB (Western Blot) (ensure identification of antigen)
• Immunogen: Recombinant Drosophila melanogaster (Fruit fly) Diap1 protein
• Conjugation: Non-conjugate
• Modification: Unmodified
• Deliverables: 1. 200ug recombinant immunogen protein/peptide (positive control).; 2. 1mL preimmune serum (negative control); 3. 10mg rabbit polyclonal antibody purified by Protein A/G.
• Quality Guarantee: 1. Antibody purity >90% confirmed by SDS-PAGE.; 2. Antibody titer > 1: 64,000 confirmed by ELISA; 3. Western Blot positive for the immunogen protein (Not applicable for synthetic peptide).
• Complementary Antibody: Customer can choose 1 FREE antibody from the list below. Please specify the catalog # when order:; * 6*His Monoclonal Antibody #MBS1491670; * DYKDDDDK tag Monoclonal Antibody #MBS1493946; * GAPDH Monoclonal Antibody #MBS1495524; * GFP Monoclonal Antibody #MBS1496050; * Myc tag Monoclonal Antibody #MBS1497694; * GST Monoclonal Antibody #MBS1497871; * Sumo tag Monoclonal Antibody #MBS1498878; * Goat Anti-Rabbit IgG (H+L) Antibody; HRP conjugated #MBS7053510; * HA-Tag Monoclonal Antibody #MBS7135631; * E-Tag Monoclonal Antibody #MBS7135632; * TUBA1A Monoclonal Antibody #MBS7135645; * TUBB Monoclonal Antibody #MBS9018332
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

NCBI and Uniprot Product Information

• NCBI GI #: 442632667
• NCBI GeneID: 39753
• NCBI Accession #: NP_001261916.1
• NCBI GenBank Nucleotide #: NM_001274987.1
• UniProt Accession #: Q24306; Q0E8E4; Q8MRM5; Q9VUX5; A4V1Z9; A9UN33
• Molecular Weight: 48,038 Da
• NCBI Official Full Name: Death-associated inhibitor of apoptosis 1, isoform D
• NCBI Official Synonym Full Names: Death-associated inhibitor of apoptosis 1
• NCBI Official Symbol: Diap1
• NCBI Official Synonym Symbols: 0736/01; 1065/03; CG12284; D-iap1; D-IAP1; diap; dIAP; Diap; DIAP; diap 1; DIAP I; diap-1; dIAP-1; Diap-1; DIAP-1; Diap-1/Th; diap1; dIap1; dIAP1; DIAP1; diap1/thread; DIAPI; DmelCG12284; E(rpr)3-1; IAP; Iap1; IAP1; l(3)72CDe; l(3)72Dc; l(3)j5C8; l(3)S030
• NCBI Protein Information: CG12284 gene product from transcript CG12284-RF
• UniProt Protein Name: Death-associated inhibitor of apoptosis 1
• Protein Family: Death-associated inhibitor of apoptosis
• UniProt Gene Name: Diap1
• UniProt Synonym Gene Names: Iap1; th

Uniprot Description

Anti-apoptotic protein which functions as a caspase regulator, using its E3 ubiquitin-protein ligase activity to smother caspase activity. Binds, ubiquitinates and inactivates initiator caspase Dronc, and effector caspases Drice and Dcp-1. Acts as a Nedd8-E3 ubiquitin-protein ligase for Drice. Suppresses apoptosis by targeting the apoptosome for ubiquitination and inactivation. Plays an important role in cell motility. Overexpression suppresses rpr and hid-dependent cell death in the eye. Interaction of Diap1 with Dronc is required to suppress Dronc-mediated cell death through Diap1-mediated ubiquitination of Dronc. Acts as a positive regulator of Wnt signaling.