Western Blot (WB)
(DI3L1 Antibody (N-term) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the DI3L1 antibody detected DI3L1 protein (arrow).)
Rabbit anti-Human, Mouse DI3L1 Polyclonal Antibody | anti-DI3L1 antibody
DI3L1, NT (DIS3L, DIS3L1, KIAA1955, DIS3-like exonuclease 1) (APC)
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Western Blot (WB)
(DI3L1 Antibody (N-term) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the DI3L1 antibody detected DI3L1 protein (arrow).)
Western Blot (WB)
(DI3L1 Antibody (N-term) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the DI3L1 antibody detected DI3L1 protein (arrow).)
Immunohistochemistry (IHC)
(DI3L1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DI3L1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(DI3L1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DI3L1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
Uniprot Description
Function: Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. Ref.6 Ref.7
Cofactor: Magnesium. Ref.6 Ref.7
Subunit structure: Component of the RNA exosome complex. The catalytically inactive RNA exosome core (Exo-9) complex is believed to associate with catalytic subunits EXOSC10, and DIS3 or DIS3L in cytoplasmic- and nuclear-specific RNA exosome complex forms.
Subcellular location: Cytoplasm Ref.6 Ref.7.
Sequence similarities: Belongs to the RNR ribonuclease family.
Sequence caution: The sequence BAB85541.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
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Product Notes
The DI3L1 dis3l (Catalog #AAA6292136) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DI3L1, NT (DIS3L, DIS3L1, KIAA1955, DIS3-like exonuclease 1) (APC) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DI3L1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), FLISA, Western Blot (WB). IHC: 1:50-100 FLISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the DI3L1 dis3l for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DI3L1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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