Western Blot (WB)
(Western blot analysis of lysates from 293 cells, using DHRS8 Antibody. The lane on the right is blocked with the synthesized peptide.)
Rabbit anti-Human DHRS8 Polyclonal Antibody | anti-DHRS8 antibody
DHRS8 Antibody
Gene Names
HSD17B11; DHRS8; PAN1B; RETSDR2; SDR16C2; 17BHSD11; 17-BETA-HSD11; 17-BETA-HSDXI
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Synonyms
DHRS8; Polyclonal Antibody; DHRS8 Antibody; Estradiol 17-beta-dehydrogenase 11; 17-beta-HSD 11; 17-beta-hydroxysteroid dehydrogenase 11; 17-beta-HSD XI; 17betaHSDXI; 17bHSD11; 17betaHSD11; Dehydrogenase/reductase SDR family member 8; Retinal short-chain dehydrogenase/reductase 2; retSDR2; Cutaneous; anti-DHRS8 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
DHRS8 Antibody detects endogenous levels of total DHRS8 protein.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
300
Applicable Applications for anti-DHRS8 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
ELISA: 1:5000
ELISA: 1:5000
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from human DHRS8.
Immunogen Range
71-120
Preparation and Storage
Stable at -20 degree C for at least 1 year.
Western Blot (WB)
(Western blot analysis of lysates from 293 cells, using DHRS8 Antibody. The lane on the right is blocked with the synthesized peptide.)
Western Blot (WB)
(Western blot analysis of lysates from 293 cells, using DHRS8 Antibody. The lane on the right is blocked with the synthesized peptide.)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
32 kDa
NCBI Official Full Name
estradiol 17-beta-dehydrogenase 11
NCBI Official Synonym Full Names
hydroxysteroid 17-beta dehydrogenase 11
NCBI Official Symbol
HSD17B11
NCBI Official Synonym Symbols
DHRS8; PAN1B; RETSDR2; SDR16C2; 17BHSD11; 17-BETA-HSD11; 17-BETA-HSDXI
NCBI Protein Information
estradiol 17-beta-dehydrogenase 11
UniProt Protein Name
Estradiol 17-beta-dehydrogenase 11
UniProt Gene Name
HSD17B11
UniProt Synonym Gene Names
DHRS8; PAN1B; SDR16C2; 17-beta-HSD 11; 17bHSD11; 17betaHSD11; 17-beta-HSD XI; 17betaHSDXI; CTCL-associated antigen HD-CL-03; retSDR2
NCBI Description
Short-chain alcohol dehydrogenases, such as HSD17B11, metabolize secondary alcohols and ketones (Brereton et al., 2001 [PubMed 11165019]).[supplied by OMIM, Jun 2009]
Uniprot Description
Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma.
Research Articles on DHRS8
Similar Products
Product Notes
The DHRS8 hsd17b11 (Catalog #AAA9506273) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DHRS8 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DHRS8 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:1000 ELISA: 1:5000. Researchers should empirically determine the suitability of the DHRS8 hsd17b11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DHRS8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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