Rabbit anti-Human DGCR6L Polyclonal Antibody | anti-DGCR6L antibody

DGCR6L, ID (DGCR6L, Protein DGCR6L, DiGeorge syndrome critical region 6-like protein) (PE)

Cat. Num. AAA6291892

• Gene Names: DGCR6L; DGCR6
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: DGCR6L; Polyclonal Antibody; ID (DGCR6L; Protein DGCR6L; DiGeorge syndrome critical region 6-like protein) (PE); DiGeorge syndrome critical region 6-like protein; anti-DGCR6L antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-DGCR6L antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: DGCR6L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-135 amino acids from the Central region of human DGCR6L.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western blot analysis of DGCR6L (arrow) using rabbit polyclonal DGCR6L Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DGCR6L gene.)

Related Product Information for anti-DGCR6L antibody

This gene, the result of a duplication at this locus, is one of two functional genes encoding nearly identical proteins that have similar expression patterns. The product of this gene is a protein that shares homology with the Drosophila gonadal protein, expressed in gonadal tissues and germ cells, and with the human laminin gamma-1 chain that functions in cell attachment and migration. This gene is located in a region of chromosome 22 implicated in the DiGeorge syndrome, one facet of a broader collection of anomalies referred to as the CATCH 22 syndrome.

Product Categories/Family for anti-DGCR6L antibody

Antibodies; Disease Markers

References

Li, X., et al. Int. J. Biochem. Cell Biol. 42(1):70-79(2010). Pfuhl, T., et al. Hum. Genet. 117(1):70-80(2005). Edelmann, L., et al. Genome Res. 11(2):208-217(2001).

NCBI and Uniprot Product Information

• NCBI GI #: 301601623
• NCBI GeneID: 85359
• NCBI Accession #: NP_150282.2
• NCBI GenBank Nucleotide #: NM_033257.3
• UniProt Accession #: Q9BY27; Q9BW33; A8K1N7; B3KMC0; D3DX29
• Molecular Weight: 24,932 Da
• NCBI Official Full Name: protein DGCR6L
• NCBI Official Synonym Full Names: DiGeorge syndrome critical region gene 6-like
• NCBI Official Symbol: DGCR6L
• NCBI Official Synonym Symbols: DGCR6
• NCBI Protein Information: protein DGCR6L; DiGeorge syndrome critical region gene 6 like; diGeorge syndrome critical region 6-like protein
• UniProt Protein Name: Protein DGCR6L
• Protein Family: Protein
• UniProt Gene Name: DGCR6L
• UniProt Entry Name: DGC6L_HUMAN

NCBI Description

This gene, the result of a duplication at this locus, is one of two functional genes encoding nearly identical proteins that have similar expression patterns. The product of this gene is a protein that shares homology with the Drosophila gonadal protein, expressed in gonadal tissues and germ cells, and with the human laminin gamma-1 chain that functions in cell attachment and migration. This gene is located in a region of chromosome 22 implicated in the DiGeorge syndrome, one facet of a broader collection of anomalies referred to as the CATCH 22 syndrome. [provided by RefSeq, Jul 2008]

Uniprot Description

DGCR6L: May play a role in neural crest cell migration into the third and fourth pharyngeal pouches. Belongs to the gonadal family.

Chromosomal Location of Human Ortholog: 22q11.21

Cellular Component: nucleus

Molecular Function: protein binding