Rabbit DDX17 Polyclonal Antibody | anti-DDX17 antibody
DDX17 Rabbit Polyclonal
Immunogen Affinity Purified
Immunogen Affinity Purified
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human kidney using MBS768528 (DDX17 antibody) at dilution of 1:100)
Immunofluorescence (IF)
(Immunofluorescent analysis of Hela cells, using DDX17 antibody MBS768528 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red) .)
Immunoprecipitation (IP)
(IP Result of anti-DDX17,P72 (IP: MBS768528, 4ug; Detection: MBS768528 1:1000) with mouse brain tissue lysate 3000ug.)
Western Blot (WB)
(HEK-293 tissue were subjected to SDS PAGE followed by western blot with MBS768528 (DDX17 antibody) at dilution of 1:1000)
NCBI and Uniprot Product Information
Uniprot Description
DDX17: RNA-dependent ATPase activity. Involved in transcriptional regulation. Transcriptional coactivator for estrogen receptor ESR1. Increases ESR1 AF-1 domain-mediated transactivation. Synergizes with DDX5 and SRA1 RNA to activate MYOD1 transcriptional activity and probably involved in skeletal muscle differentiation. Required for zinc-finger antiviral protein ZC3HAV1-mediated mRNA degradation. Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA-binding; Nucleolus; Helicase; EC 3.6.4.13; Transcription, coactivator/corepressor; Nuclear receptor co-regulator; Spliceosome; RNA processing
Chromosomal Location of Human Ortholog: 22q13.1
Cellular Component: membrane; nucleolus; nucleoplasm; nucleus
Molecular Function: ATP binding; ATP-dependent RNA helicase activity; estrogen receptor binding; protein binding; RNA binding; RNA helicase activity; RNA-dependent ATPase activity; transcription coactivator activity
Biological Process: positive regulation of estrogen receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; RNA processing; RNA secondary structure unwinding; transcription, DNA-dependent
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Product Notes
The DDX17 ddx17 (Catalog #AAA768528) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DDX17 Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DDX17 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the DDX17 ddx17 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DDX17, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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