Rabbit anti-Human; Mouse DDRGK1 Polyclonal Antibody | anti-DDRGK1 antibody
DDRGK1 Antibody
Gene Names
DDRGK1; UFBP1; SEMDSH; C20orf116; dJ1187M17.3
Reactivity
Human; Mouse
Applications
Western Blot
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
DDRGK1; Polyclonal Antibody; DDRGK1 Antibody; DDRGK1 Antibody - N-terminal; 1110001I20Rik; 2600009E05Rik; C20orf116; Chromosome 20 open reading frame 116; Dashurin; DDRGK domain containing 1; DDRGK domain containing protein 1; DDRGK domain-containing protein 1; DDRGK_HUMAN; Ddrgk1; dJ1187M17.3; MGC2592; OTTHUMP00000030088; RGD1309979; RP23-100C5.9; UFM1-binding and PCI domain-containing protein 1;; anti-DDRGK1 antibody
Host
Rabbit
Reactivity
Human; Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
DDRGK1 Antibody detects endogenous levels of DDRGK1.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid
Concentration
1mg/ml (varies by lot)
Sequence Length
314
Applicable Applications for anti-DDRGK1 antibody
Western Blot (WB)
Application Notes
WB 1:500-1:2000
Immunogen
A synthesized peptide derived from human DDRGK1.
Fragment
Fab fragment
Conjugation
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C. Stable for 12 months from date of receipt.
Post Translational Modifications
Ubiquitinated. Ubiquitination probably triggers proteasomal degradation and is negatively regulated by UFL1, the enzyme involved in the ufmylation of DDRGK1.Ufmylated. Conjugated to ubiquitin-like protein UFM1, probably at Lys-267 by UFL1.
Preparation and Storage
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 degree C. Stable for 12 months from date of receipt.
Related Product Information for anti-DDRGK1 antibody
Protein which interacts with the E3 UFM1-protein ligase UFL1 and one of its substrates TRIP4 and is required for TRIP4 ufmylation. Through TRIP4 ufmylation may regulate nuclear receptors-mediated transcription (PubMed:25219498). May play a role in NF-kappa-B-mediated transcription through regulation of the phosphorylation and the degradation of NFKBIA, the inhibitor of NF-kappa-B (PubMed:23675531). May also play a role in the cellular response to endoplasmic reticulum stress (By similarity).
Similarity: Belongs to the DDRGK1 family.
Similarity: Belongs to the DDRGK1 family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed Mol.Wt.: 36 kDa. Predicted Mol.Wt.: 36kDa.
NCBI Official Full Name
DDRGK domain-containing protein 1
NCBI Official Synonym Full Names
DDRGK domain containing 1
NCBI Official Symbol
DDRGK1
NCBI Official Synonym Symbols
UFBP1; SEMDSH; C20orf116; dJ1187M17.3
NCBI Protein Information
DDRGK domain-containing protein 1
UniProt Protein Name
DDRGK domain-containing protein 1
UniProt Gene Name
DDRGK1
UniProt Synonym Gene Names
C20orf116
UniProt Entry Name
DDRGK_HUMAN
NCBI Description
The protein encoded by this gene interacts with components of the ubiquitin fold modifier 1 conjugation pathway and helps prevent apoptosis in ER-stressed secretory tissues. In addition, the encoded protein regulates nuclear factor-κB activity. [provided by RefSeq, Dec 2015]
Research Articles on DDRGK1
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Product Notes
The DDRGK1 ddrgk1 (Catalog #AAA9611684) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DDRGK1 Antibody reacts with Human; Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DDRGK1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB 1:500-1:2000. Researchers should empirically determine the suitability of the DDRGK1 ddrgk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DDRGK1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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