Mouse anti-Human DCUN1D3 Polyclonal Antibody | anti-DCUN1D3 antibody

DCUN1D3 (DCN1-like Protein 3, DCUN1 Domain-containing Protein 3, Defective in Cullin Neddylation Protein 1-like Protein 3)

Cat. Num. AAA6010213

• Gene Names: DCUN1D3; 44M2.4
• Reactivity: Human
• Applications: Western Blot, Immunofluorescence
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: DCUN1D3; Polyclonal Antibody; DCUN1D3 (DCN1-like Protein 3; DCUN1 Domain-containing Protein 3; Defective in Cullin Neddylation Protein 1-like Protein 3); Anti -DCUN1D3 (DCN1-like Protein 3; anti-DCUN1D3 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human DCUN1D3.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MGQCVTKCKNPSSTLGSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQLPTSSGDAGRESKSNAEESSLQRLEELFRRYKDEREDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATMCKFTRKEFFDGCKAISADSIDGICARFPSLLTEAKQEDKFKDLYRFTFQFGLDSEEGQRSLHREIAIALWKLVFTQNNPPVLDQWLNFLTENPSGIKGISRDTWNMFLNFTQVIGPDLSNYSEDEAWPSLFDTFVEWEMERRKREGEGRGALSSGPEGLCPEEQT

• Applicable Applications for anti-DCUN1D3 antibody: Western Blot (WB), Immunofluorescence (IF)
• Application Notes: Suitable for use in Immunofluorescence and Western Blot.; Dilution: Immunofluorescence: 10ug/ml
• Immunogen: Full length human DCUN1D3, aa1-304 (NP_775746.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of DCUN1D3 expression in transfected 293T cell line by DCUN1D3 polyclonal antibody. Lane 1: DCUN1D3 transfected lysate (33.44kD). Lane 2: Non-transfected lysate.)

Immunofluorescence (IF)

(Immunofluorescence of purified antibody to DCUN1D3 on HeLa cell. [antibody concentration 10ug/ml].)

Product Categories/Family for anti-DCUN1D3 antibody

Antibodies; Abs to Cullin

NCBI and Uniprot Product Information

• NCBI GI #: 27735047
• NCBI GeneID: 123879
• NCBI Accession #: NP_775746.1
• NCBI GenBank Nucleotide #: NM_173475.2
• UniProt Accession #: Q8IWE4; B3KVY4
• Molecular Weight: 34,291 Da
• NCBI Official Full Name: DCN1-like protein 3
• NCBI Official Synonym Full Names: DCN1, defective in cullin neddylation 1, domain containing 3
• NCBI Official Symbol: DCUN1D3
• NCBI Official Synonym Symbols: 44M2.4
• NCBI Protein Information: DCN1-like protein 3; DCUN1 domain-containing protein 3; defective in cullin neddylation protein 1-like protein 3
• UniProt Protein Name: DCN1-like protein 3
• Protein Family: DCN1-like protein
• UniProt Gene Name: DCUN1D3
• UniProt Entry Name: DCNL3_HUMAN

Uniprot Description

DCUN1D3: Potently stimulates the neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes from the NEDD8- conjugating E2 enzyme UBE2F. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity

Chromosomal Location of Human Ortholog: 16p12.3

Cellular Component: perinuclear region of cytoplasm

Biological Process: positive regulation of apoptosis; response to gamma radiation; negative regulation of cell growth; response to UV-C