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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human cervix using MBS768446 (KRT4 antibody) at dilution of 1:100)

Rabbit Cytokeratin 4 Polyclonal Antibody | anti-KRT4 antibody

Cytokeratin 4 Rabbit Polyclonal

Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
Cytokeratin 4; Polyclonal Antibody; Cytokeratin 4 Rabbit Polyclonal; anti-KRT4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
408
Applicable Applications for anti-KRT4 antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
Immunogen
Keratin 4
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human cervix using MBS768446 (KRT4 antibody) at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human cervix using MBS768446 (KRT4 antibody) at dilution of 1:100)

Western Blot (WB)

(A431 cells were subjected to SDS PAGE followed by western blot with MBS768446 (KRT4 Antibody) at dilution of 1:600)

Western Blot (WB) (A431 cells were subjected to SDS PAGE followed by western blot with MBS768446 (KRT4 Antibody) at dilution of 1:600)

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
57,285 Da
NCBI Official Full Name
cytokeratin 4 (408 AA), partial
UniProt Protein Name
Keratin, type II cytoskeletal 4
Protein Family
UniProt Gene Name
KRT4
UniProt Synonym Gene Names
CYK4; CK-4; K4
UniProt Entry Name
K2C4_HUMAN

Uniprot Description

K4: Heterotetramer of two type I and two type II keratins. Keratin-4 is generally associated with keratin-13. Detected in the suprabasal layer of the stratified epithelium of the esophagus, exocervix, vagina, mouth and lingual mucosa, and in cells and cell clusters in the mucosa and serous gland ducts of the esophageal submucosa. Expressed widely in the exocervix and esophageal epithelium, with lowest levels detected in the basal cell layer. Belongs to the intermediate filament family.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 12q13.13

Cellular Component: cell surface; intermediate filament; intermediate filament cytoskeleton; keratin filament; nucleus

Molecular Function: protein binding; structural molecule activity

Biological Process: cytoskeleton organization and biogenesis; epithelial cell differentiation; negative regulation of epithelial cell proliferation

Disease: White Sponge Nevus 1

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Product Notes

The Cytokeratin 4 krt4 (Catalog #AAA768446) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Cytokeratin 4 Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Cytokeratin 4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the Cytokeratin 4 krt4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytokeratin 4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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