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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human colon tissue slide using MBS768440 (CK19 Antibody) at dilution of 1:200)

Rabbit Cytokeratin 19 Polyclonal Antibody | anti-KRT19 antibody

Cytokeratin 19 Rabbit Polyclonal

Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
Cytokeratin 19; Polyclonal Antibody; Cytokeratin 19 Rabbit Polyclonal; anti-KRT19 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
9
Applicable Applications for anti-KRT19 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Immunogen
Keratin 19
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human colon tissue slide using MBS768440 (CK19 Antibody) at dilution of 1:200)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human colon tissue slide using MBS768440 (CK19 Antibody) at dilution of 1:200)

Western Blot (WB)

(A431 cells were subjected to SDS PAGE followed by western blot with MBS768440 (KRT19 antibody) at dilution of 1:1000)

Western Blot (WB) (A431 cells were subjected to SDS PAGE followed by western blot with MBS768440 (KRT19 antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

NCBI GI #
Molecular Weight
44,106 Da
NCBI Official Full Name
cytokeratin 19, partial
UniProt Protein Name
Keratin, type I cytoskeletal 19
Protein Family
UniProt Gene Name
KRT19
UniProt Synonym Gene Names
CK-19; K19
UniProt Entry Name
K1C19_HUMAN

Uniprot Description

K19: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 19 differs from all other IF proteins in lacking the C-terminal tail domain. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 17q21.2

Cellular Component: costamere; dystrophin-associated glycoprotein complex; intermediate filament; plasma membrane; sarcolemma; Z disc

Molecular Function: protein binding; protein complex binding; structural constituent of cytoskeleton; structural constituent of muscle

Biological Process: Notch signaling pathway; response to estrogen stimulus; sarcomere organization; viral reproduction

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Product Notes

The Cytokeratin 19 krt19 (Catalog #AAA768440) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Cytokeratin 19 Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Cytokeratin 19 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Researchers should empirically determine the suitability of the Cytokeratin 19 krt19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytokeratin 19, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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