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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human liver cancer using MBS1494772 at dilution 1:100)

Rabbit anti-Human Cytoglobin Polyclonal Antibody | anti-CYGB antibody

Rabbit anti-human Cytoglobin polyclonal Antibody(CYGB)

Gene Names
CYGB; HGB; STAP
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
Cytoglobin; Polyclonal Antibody; Rabbit anti-human Cytoglobin polyclonal Antibody(CYGB); Histoglobin; HGb; Stellate cell activation-associated protein; CYGB; STAP; anti-CYGB antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
190
Applicable Applications for anti-CYGB antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: IHC:1:20-1:200
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Cytoglobin protein (1-190aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-34598 / sc-34596 / sc-34598 / sc-34596 / sc-66855
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human liver cancer using MBS1494772 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human liver cancer using MBS1494772 at dilution 1:100)
Related Product Information for anti-CYGB antibody
May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
21,405 Da
NCBI Official Full Name
cytoglobin
NCBI Official Synonym Full Names
cytoglobin
NCBI Official Symbol
CYGB
NCBI Official Synonym Symbols
HGB; STAP
NCBI Protein Information
cytoglobin
UniProt Protein Name
Cytoglobin
Protein Family
UniProt Gene Name
CYGB
UniProt Synonym Gene Names
STAP; HGb
UniProt Entry Name
CYGB_HUMAN

NCBI Description

This gene encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. This gene is located on chromosome 17 in the same region as a retinal gene which is mutated in progressive rod-cone degeneration, but in the opposite orientation. [provided by RefSeq, Jan 2012]

Uniprot Description

CYGB: May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer. Belongs to the globin family.

Chromosomal Location of Human Ortholog: 17q25

Cellular Component: cell soma; cytosol; neuron projection

Molecular Function: catalase activity; fatty-acid peroxidase activity; heme binding; iron ion binding; nitric oxide dioxygenase activity; oxygen binding; oxygen transporter activity; peroxidase activity; protein binding

Biological Process: fatty acid oxidation; negative regulation of collagen biosynthetic process; nitric oxide metabolic process; oxygen transport; regulation of nitric-oxide synthase activity; response to hypoxia; response to oxidative stress

Research Articles on CYGB

Similar Products

Product Notes

The CYGB cygb (Catalog #AAA1494772) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Cytoglobin polyclonal Antibody(CYGB) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Cytoglobin can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Recommended dilution: IHC:1:20-1:200. Researchers should empirically determine the suitability of the CYGB cygb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytoglobin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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