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Western Blot (WB) (Western blot analysis of extracts from HeLa cells, using Cytochrome P450 4F11 antibody.The lane on the left is treated with the antigen-specific peptide.)

Rabbit anti-Human Cytochrome P450 4F11 Polyclonal Antibody | anti-CYP4F11 antibody

Cytochrome P450 4F11 Antibody

Gene Names
CYP4F11; CYPIVF11
Reactivity
Human
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
Cytochrome P450 4F11; Polyclonal Antibody; Cytochrome P450 4F11 Antibody; cytochrome P450; family 4; subfamily F; polypeptide 11; subfamily IVF; anti-CYP4F11 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Cytochrome P450 4F11 antibody detects endogenous levels of total Cytochrome P450 4F11
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
524
Applicable Applications for anti-CYP4F11 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:1000
Immunogen
A synthesized peptide
Subcellular Location
Endoplasmic Reticulum Membrane; Single-Pass Membrane Protein
Tissue Specificity
Expressed mainly in human liver, followed by kidney, heart, and skeletal muscle.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of extracts from HeLa cells, using Cytochrome P450 4F11 antibody.The lane on the left is treated with the antigen-specific peptide.)

Western Blot (WB) (Western blot analysis of extracts from HeLa cells, using Cytochrome P450 4F11 antibody.The lane on the left is treated with the antigen-specific peptide.)
Related Product Information for anti-CYP4F11 antibody
Function: Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:24138531). Catalyzes omega-hydroxylation of 3-hydroxy fatty acids, such as 3-hydroxypalmitate, 3-hydroxyoleate, 3-hydroxyarachidonate, and 3-hydroxystearate (PubMed:18065749, PubMed:19932081). Oxidizes drugs such as erythromycin, benzphetamine, ethylmorphine, chlorpromazine and imipramine (PubMed:15364545).
Similarity: Belongs to the cytochrome P450 family.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 60 kD
Predicted: 61 kDa
NCBI Official Full Name
phylloquinone omega-hydroxylase CYP4F11
NCBI Official Synonym Full Names
cytochrome P450 family 4 subfamily F member 11
NCBI Official Symbol
CYP4F11
NCBI Official Synonym Symbols
CYPIVF11
NCBI Protein Information
phylloquinone omega-hydroxylase CYP4F11
UniProt Protein Name
Phylloquinone omega-hydroxylase CYP4F11
UniProt Gene Name
CYP4F11
UniProt Synonym Gene Names
CYPIVF11

NCBI Description

This gene, CYP4F11, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F2, is approximately 16 kb away. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:24138531). Catalyzes omega-hydroxylation of 3-hydroxy fatty acids, such as 3-hydroxypalmitate, 3-hydroxyoleate, 3-hydroxyarachidonate, and 3-hydroxystearate (PubMed:18065749, PubMed:19932081). Oxidizes drugs such as erythromycin, benzphetamine, ethylmorphine, chlorpromazine and imipramine (PubMed:15364545).

Research Articles on CYP4F11

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Product Notes

The CYP4F11 cyp4f11 (Catalog #AAA9606204) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Cytochrome P450 4F11 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Cytochrome P450 4F11 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the CYP4F11 cyp4f11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytochrome P450 4F11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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