Rabbit anti-Human, Mouse CYP4F11 Polyclonal Antibody | anti-CYP4F11 antibody

CYP4F11-Specific Rabbit Polyclonal

Cat. Num. AAA768403

• Gene Names: CYP4F11; CYPIVF11
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: CYP4F11; Polyclonal Antibody; CYP4F11-Specific Rabbit Polyclonal; anti-CYP4F11 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 524

• Applicable Applications for anti-CYP4F11 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Immunogen: Cytochrome P450, family 4, subfamily F, polypeptide 11
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human hepatocirrhosis using MBS768403 (CYP4F11-Specific antibody) at dilution of 1:50)

Western Blot (WB)

(mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with MBS768403 (CYP4F11-Specific antibody) at dilution of 1:600)

NCBI and Uniprot Product Information

• NCBI GI #: 10303605
• NCBI GeneID: 57834
• Molecular Weight: 60,146 Da
• NCBI Official Full Name: CYP4F11
• NCBI Official Synonym Full Names: cytochrome P450 family 4 subfamily F member 11
• NCBI Official Symbol: CYP4F11
• NCBI Official Synonym Symbols: CYPIVF11
• NCBI Protein Information: phylloquinone omega-hydroxylase CYP4F11
• UniProt Protein Name: Phylloquinone omega-hydroxylase CYP4F11
• Protein Family: Phylloquinone omega-hydroxylase
• UniProt Gene Name: CYP4F11
• UniProt Synonym Gene Names: CYPIVF11
• UniProt Entry Name: CP4FB_HUMAN

NCBI Description

This gene, CYP4F11, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F2, is approximately 16 kb away. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

CYP4F11: a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F2, is approximately 16 kb away. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Protein type: Oxidoreductase; Membrane protein, integral; EC 1.14.13.194

Chromosomal Location of Human Ortholog: 19p13.1

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Molecular Function: heme binding; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen

Biological Process: blood coagulation; inflammatory response; menaquinone catabolic process; phylloquinone catabolic process; vitamin K catabolic process