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Immunohistochemistry (IHC) (Anti-CYP2U1 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Rabbit CYP2U1 Polyclonal Antibody | anti-CYP2U1 antibody

Anti-CYP2U1 Antibody (aa281-330) IHC-plus

Gene Names
CYP2U1; SPG49; SPG56; P450TEC
Reactivity
Mouse, Rat, Human
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Immunoaffinity purified
Synonyms
CYP2U1; Polyclonal Antibody; Anti-CYP2U1 Antibody (aa281-330) IHC-plus; Rabbit Polyclonal (IgG) to Human CYP2U1; Human CYP2U1; p450TEC; SPG49; Cytochrome P450 2U1; anti-CYP2U1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Rat, Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Cytochrome P450 2U1 Antibody detects endogenous levels of total Cytochrome P450 2U1 protein.
Purity/Purification
Immunoaffinity purified
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Concentration
1 mg/ml (varies by lot)
Sequence Length
544
Applicable Applications for anti-CYP2U1 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA)
Application Notes
ELISA (1:20000)
IHC-P (10 ug/ml)
WB (1:500 - 1:1000)
Immunogen
CYP2U1 antibody was raised against synthetic peptide from human Cytochrome P450 2U1 (aa281-330).
Immunogen Description
Synthetic peptide from human Cytochrome P450 2U1 (aa281-330).
Antigen Modification
aa281-330
Target Species
Human
Preparation and Storage
Store at -20 degree C for up to one year.

Immunohistochemistry (IHC)

(Anti-CYP2U1 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Immunohistochemistry (IHC) (Anti-CYP2U1 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Western Blot (WB)

(Western blot of extracts from HeLa/Lovo cells, using Cytochrome P450 2U1 Antibody. The lane on the right is treated with the synthesized peptide.)

Western Blot (WB) (Western blot of extracts from HeLa/Lovo cells, using Cytochrome P450 2U1 Antibody. The lane on the right is treated with the synthesized peptide.)
Related Product Information for anti-CYP2U1 antibody
CYP2U1 Antibody, p450TEC Antibody, SPG49 Antibody, Cytochrome P450 2U1 Antibody Description: Catalyzes the hydroxylation of arachidonic acid, docosahexaenoic acid and other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
18,578 Da
NCBI Official Full Name
cytochrome P450 2U1
NCBI Official Synonym Full Names
cytochrome P450 family 2 subfamily U member 1
NCBI Official Symbol
CYP2U1
NCBI Official Synonym Symbols
SPG49; SPG56; P450TEC
NCBI Protein Information
cytochrome P450 2U1
UniProt Protein Name
Cytochrome P450 2U1
Protein Family
UniProt Gene Name
CYP2U1
UniProt Entry Name
CP2U1_HUMAN

NCBI Description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a hydroxylase that metabolizes arachidonic acid, docosahexaenoic acid, and other long chain fatty acids. [provided by RefSeq, Jul 2008]

Uniprot Description

CYP2U1: Catalyzes the hydroxylation of arachidonic acid, docosahexaenoic acid and other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes. Belongs to the cytochrome P450 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Oxidoreductase; Membrane protein, integral; Lipid Metabolism - arachidonic acid; Membrane protein, multi-pass; EC 1.14.14.1

Chromosomal Location of Human Ortholog: 4q25

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Molecular Function: heme binding; iron ion binding; steroid hydroxylase activity

Biological Process: arachidonic acid metabolic process; xenobiotic metabolic process

Disease: Spastic Paraplegia 56, Autosomal Recessive

Research Articles on CYP2U1

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Product Notes

The CYP2U1 cyp2u1 (Catalog #AAA249956) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CYP2U1 Antibody (aa281-330) IHC-plus reacts with Mouse, Rat, Human and may cross-react with other species as described in the data sheet. AAA Biotech's CYP2U1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA). ELISA (1:20000) IHC-P (10 ug/ml) WB (1:500 - 1:1000). Researchers should empirically determine the suitability of the CYP2U1 cyp2u1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CYP2U1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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