Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Rabbit anti-Rat CYP2D1 Polyclonal Antibody | anti-CYP2D1 antibody

CYP2D1 antibody

Gene Names
Cyp2d1; Cyp2d9
Reactivity
Rat
Applications
Immunohistochemistry, Western Blot
Synonyms
CYP2D1; Polyclonal Antibody; CYP2D1 antibody; Polyclonal CYP2D1; Anti-CYP2D1; Cytochrome P-450; Cytochrome P 450; Rat CYP2D1; Cytochrome P450 2D1; Cytochrome P450; anti-CYP2D1 antibody
Ordering
Host
Rabbit
Reactivity
Rat
Clonality
Polyclonal
Specificity
Rat
Form/Format
Neat serum with no preservatives.
Sequence Length
504
Applicable Applications for anti-CYP2D1 antibody
Immunohistochemistry (IHC), Western Blot (WB)
Biological Significance
The cytochrome P450 superfamily (officially abbreviated as CYP) is a large and diverse group of enzymes. The function of most CYP enzymes is to catalyze the oxidation of organic substances. The substrates of CYP enzymes include metabolic intermediates such as lipids and steroidal hormones, as well as xenobiotic substances such as drugs and other toxic chemicals. Rat CYP2D1, the homologue of human CYP2D6, has been shown to catalyse the conversion of hydrocodone to hydromorphone, and in rat liver microsomes it participates in the conversion of ethylmorphine to codeine and morphine. Its regional distribution in the rat brain has been described. Mutation in the cyp2D6 gene has been reported to be associated with PD10.
Immunogen
CYP2D1 antibody was raised in rabbit using a synthetic peptide as the immunogen.
Preparation and Storage
Aliquot and store at -20 degree C. Avoid repeated Freeze/Thaw cycles
Related Product Information for anti-CYP2D1 antibody
Rabbit polyclonal CYP2D1 antibody
Product Categories/Family for anti-CYP2D1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
57,175 Da
NCBI Official Full Name
Cytochrome P450 2D1
NCBI Official Synonym Full Names
cytochrome P450, family 2, subfamily d, polypeptide 1
NCBI Official Symbol
Cyp2d1
NCBI Official Synonym Symbols
Cyp2d9
NCBI Protein Information
cytochrome P450 2D1
UniProt Protein Name
Cytochrome P450 2D1
Protein Family
UniProt Gene Name
Cyp2d1
UniProt Synonym Gene Names
Cyp2d-1; Cyp2d9
UniProt Entry Name
CP2D1_RAT

NCBI Description

debrisoquine 4-hydroxylase [RGD, Feb 2006]

Uniprot Description

CYP2D1: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Belongs to the cytochrome P450 family.

Protein type: Oxidoreductase; EC 1.14.14.1

Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle; cytoplasm

Molecular Function: iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; heme binding; arachidonic acid epoxygenase activity; steroid hydroxylase activity; oxygen binding; monooxygenase activity

Biological Process: response to drug; response to organic substance; xenobiotic metabolic process; exogenous drug catabolic process; arachidonic acid metabolic process; response to organic cyclic substance

Research Articles on CYP2D1

Similar Products

Product Notes

The CYP2D1 cyp2d1 (Catalog #AAA534511) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CYP2D1 antibody reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CYP2D1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the CYP2D1 cyp2d1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CYP2D1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.