Western Blot (WB)
(Western Blot analysis of extracts of various cell lines, using CYP2C9 antibody.)
Rabbit anti-Human, Mouse CYP2C9 Polyclonal Antibody | anti-CYP2C9 antibody
CYP2C9 Polyclonal Antibody
Gene Names
CYP2C9; CPC9; CYP2C; CYP2C10; CYPIIC9; P450IIC9
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry, Immunofluorescence
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
CYP2C9; Polyclonal Antibody; CYP2C9 Polyclonal Antibody; Cytochrome P450 2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC9; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase; CYP2C10; anti-CYP2C9 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
CYP2C9 polyclonal antibody detects endogenous levels of CYP2C9 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
490
Applicable Applications for anti-CYP2C9 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
IF: 1:10-1:100
IHC: 1:50-1:200
IF: 1:10-1:100
Immunogen
Recombinant full length Human CYP2C9.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot analysis of extracts of various cell lines, using CYP2C9 antibody.)
Western Blot (WB)
(Western Blot analysis of extracts of various cell lines, using CYP2C9 antibody.)
Related Product Information for anti-CYP2C9 antibody
Cytochrome P450, family 2, subfamily C polypeptides 9 and 19 are part of the CYP2C subfamily and are responsible for metabolizing many important drugs. CYP2C19 accounts for about 20% of the cytochrome p450 in adult liver. CYP2C9 contributes to the metabolism of fatty acids, prostanoids, and steroid hormones, and it may catalyze potentially toxic bioactivation reactions. A significant negative correlation (r = -0.572, P <.01) between enzyme activity and age was observed for CYP2C19, but there were no sex differences.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 63kDa
NCBI Official Full Name
cytochrome P450 2C9
NCBI Official Synonym Full Names
cytochrome P450 family 2 subfamily C member 9
NCBI Official Symbol
CYP2C9
NCBI Official Synonym Symbols
CPC9; CYP2C; CYP2C10; CYPIIC9; P450IIC9
NCBI Protein Information
cytochrome P450 2C9
UniProt Protein Name
Cytochrome P450 2C9
Protein Family
UniProt Gene Name
CYP2C9
UniProt Synonym Gene Names
CYP2C10
UniProt Entry Name
CP2C9_HUMAN
NCBI Description
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]
Research Articles on CYP2C9
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Product Notes
The CYP2C9 cyp2c9 (Catalog #AAA3011785) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CYP2C9 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CYP2C9 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:10-1:100. Researchers should empirically determine the suitability of the CYP2C9 cyp2c9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CYP2C9, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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