Western Blot (WB)
(Western Blot: (Raji cells))
Rabbit anti-Rat Cyclic ADP Ribose Hydrolase Polyclonal Antibody | anti-cADPRH antibody
Polyclonal Antibody to Cyclic ADP Ribose Hydrolase (cADPRH)
Immunohistochemistry: 5-20ug/mL;1:50-200
Immunocytochemistry: 5-20ug/mL;1:50-200
Optimal working dilutions must be determined by end user.
Western Blot (WB)
(Western Blot: (Raji cells))
Western Blot (WB)
(Western Blot: (Raji cells))
Western Blot (WB)
(Western Blot: (Rat serum))
Western Blot (WB)
(Western Blot: (Rat serum))
Immunohistochemistry (IHC)
(DAB staining on IHC-P. Samples: Rat Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P. Samples: Rat Tissue))
NCBI and Uniprot Product Information
NCBI Description
ADP-ribosyl cyclase enzyme involved in regulation of cellular calcium levels [RGD, Feb 2006]
Uniprot Description
CD38: Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. Belongs to the ADP-ribosyl cyclase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Apoptosis; Cell cycle regulation; Cell surface; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; EC 2.4.99.20; EC 3.2.2.6; Hydrolase; Lyase; Membrane protein, integral
Chromosomal Location of Human Ortholog: 14q21
Cellular Component: cell surface; integral component of membrane; intracellular membrane-bound organelle; membrane; nucleus; plasma membrane
Molecular Function: hydrolase activity, acting on glycosyl bonds; NAD(P)+ nucleosidase activity; NAD+ nucleosidase activity; phosphorus-oxygen lyase activity; transferase activity
Biological Process: B cell receptor signaling pathway; elevation of cytosolic calcium ion concentration; female pregnancy; negative regulation of apoptosis; negative regulation of bone resorption; negative regulation of transcription, DNA-dependent; positive regulation of B cell proliferation; positive regulation of cell growth; positive regulation of insulin secretion; positive regulation of transcription, DNA-templated; positive regulation of vasoconstriction; response to cytokine; response to drug; response to estradiol; response to hormone; response to hydroperoxide; response to hypoxia; response to progesterone; response to retinoic acid
Research Articles on cADPRH
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Product Notes
The cADPRH cd38 (Catalog #AAA2028112) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Cyclic ADP Ribose Hydrolase (cADPRH) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Cyclic ADP Ribose Hydrolase can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.5-2ug/mL;1:500-2000 Immunohistochemistry: 5-20ug/mL;1:50-200 Immunocytochemistry: 5-20ug/mL;1:50-200 Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the cADPRH cd38 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cyclic ADP Ribose Hydrolase, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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