Rabbit CXCR3 Polyclonal Antibody | anti-CXCR3 antibody
CXCR3 polyclonal antibody
Gene Names
Cxcr3; Cd183; Cmkar3
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Guinea Pig
Applications
Flow Cytometry, Functional Assay
Purity
affinity purified by Protein A
Synonyms
CXCR3; Polyclonal Antibody; CXCR3 polyclonal antibody; CXC-R3; Interferon-inducible protein 10 receptor; IP-10 receptor; CKR-L2; CD183 antigen; G protein-coupled receptor 9; C-X-C Chemokine receptor; CD183; CXC Motif Receptor 3; CKRL2; CMKAR3; G Protein Coupled Receptor 9; GPR9; IP10; IP10R; MIGR; CXCR3_HUMAN; anti-CXCR3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Guinea Pig
Clonality
Polyclonal
Specificity
CXCR3 polyclonal Antibody detects endogenous levels of CXCR3 protein.
Purity/Purification
affinity purified by Protein A
Form/Format
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Applicable Applications for anti-CXCR3 antibody
Flow Cytometry (FC/FACS/FCM)
Application Notes
FC/FACS/FCM: 2ug/Test
Immunogen
KLH conjugated synthetic peptide derived from mouse CXCR3:301-367/367
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Related Product Information for anti-CXCR3 antibody
This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011].
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
41,018 Da
NCBI Official Full Name
C-X-C chemokine receptor type 3
NCBI Official Synonym Full Names
chemokine (C-X-C motif) receptor 3
NCBI Official Symbol
Cxcr3
NCBI Official Synonym Symbols
Cd183; Cmkar3
NCBI Protein Information
C-X-C chemokine receptor type 3
UniProt Protein Name
C-X-C chemokine receptor type 3
Protein Family
UniProt Gene Name
Cxcr3
UniProt Synonym Gene Names
Cmkar3; CXC-R3; CXCR-3; IP-10 receptor
NCBI Description
This gene encodes a transmembrane protein that functions as a receptor for C-X-R chemokines. Signalling through this protein regulates a variety of biological processes, including inflammation, immunity, and would healing. This protein also plays a role in tumor growth and metastasis. [provided by RefSeq, May 2015]
Uniprot Description
Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Probably promotes cell chemotaxis response (). Binds to CCL21.
Research Articles on CXCR3
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Product Notes
The CXCR3 cxcr3 (Catalog #AAA3012673) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CXCR3 polyclonal antibody reacts with Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Guinea Pig and may cross-react with other species as described in the data sheet. AAA Biotech's CXCR3 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS/FCM). FC/FACS/FCM: 2ug/Test. Researchers should empirically determine the suitability of the CXCR3 cxcr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CXCR3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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