Immunohistochemistry (IHC)
(Immunohistochemistry with Spleen tissue at an antibody concentration of 5ug/ml using anti-CXCL14 antibody )
Rabbit CXCL14 Polyclonal Antibody | anti-CXCL14 antibody
CXCL14 antibody - middle region
Immunohistochemistry (IHC)
(Immunohistochemistry with Spleen tissue at an antibody concentration of 5ug/ml using anti-CXCL14 antibody )
Immunohistochemistry (IHC)
(Immunohistochemistry with Spleen tissue at an antibody concentration of 5ug/ml using anti-CXCL14 antibody )
Western Blot (WB)
(WB Suggested Anti-CXCL14 Antibody Titration: 1 ug/mlPositive Control: HepG2 cell lysate)
Western Blot (WB)
(WB Suggested Anti-CXCL14 Antibody Titration: 1 ug/mlPositive Control: HepG2 cell lysate)
Target Description: CXCL14 belongs to the cytokine family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation.
NCBI and Uniprot Product Information
NCBI Description
This antimicrobial gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation. [provided by RefSeq, Sep 2014]
Uniprot Description
CXCL14: Potent chemoattractant for neutrophils, and weaker for dendritic cells. Not chemotactic for T-cells, B-cells, monocytes, natural killer cells or granulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays. Belongs to the intercrine alpha (chemokine CxC) family.
Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Chemokine; Secreted
Chromosomal Location of Human Ortholog: 5q31
Cellular Component: Golgi apparatus; extracellular space
Molecular Function: chemokine activity
Biological Process: cell-cell signaling; immune response; signal transduction; negative regulation of myoblast differentiation; chemotaxis; inner ear development
Research Articles on CXCL14
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Product Notes
The CXCL14 cxcl14 (Catalog #AAA3224411) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CXCL14 antibody - middle region reacts with Cow, Dog, Guinea Pig, Horse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CXCL14 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the CXCL14 cxcl14 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: PHCEEKMVII TTKSVSRYRG QEHCLHPKLQ STKRFIKWYN AWNEKRRVYE. It is sometimes possible for the material contained within the vial of "CXCL14, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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