Rabbit anti-Human CUTC Polyclonal Antibody | anti-CUTC antibody

CUTC, ID (CUTC, Copper homeostasis protein cutC homolog) (FITC)

Cat. Num. AAA6290092

• Gene Names: CUTC; CGI-32
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: CUTC; Polyclonal Antibody; ID (CUTC; Copper homeostasis protein cutC homolog) (FITC); Copper homeostasis protein cutC homolog; anti-CUTC antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-CUTC antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: CUTC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the Central region of human CUTC.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(CUTC Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CUTC antibody detected the CUTC protein (arrow).)

Related Product Information for anti-CUTC antibody

Members of the CUT family of copper transporters are associated with copper homeostasis and are involved in the uptake, storage, delivery, and efflux of copper (Gupta et al., 1995 [PubMed 7635807]; Li et al., 2005 [PubMed 16182249]).

Product Categories/Family for anti-CUTC antibody

Antibodies; Proteins

References

Li, Y., et al. J. Struct. Biol. 169(3):399-405(2010). Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005). Li, J., et al. Biochem. Biophys. Res. Commun. 337(1):179-183(2005). Andersen, J.S., et al. Nature 433(7021):77-83(2005). Gupta, S.D., et al. J. Bacteriol. 177(15):4207-4215(1995).

NCBI and Uniprot Product Information

• NCBI GI #: 148596990
• NCBI GeneID: 51076
• NCBI Accession #: NP_057044.2
• NCBI GenBank Nucleotide #: NM_015960.2
• UniProt Accession #: Q9NTM9; Q5TCZ8; Q9Y321
• Molecular Weight: 29,341 Da
• NCBI Official Full Name: copper homeostasis protein cutC homolog
• NCBI Official Synonym Full Names: cutC copper transporter
• NCBI Official Symbol: CUTC
• NCBI Official Synonym Symbols: CGI-32
• NCBI Protein Information: copper homeostasis protein cutC homolog; cutC copper transporter homolog
• UniProt Protein Name: Copper homeostasis protein cutC homolog
• Protein Family: CutC-like protein
• UniProt Gene Name: CUTC
• UniProt Entry Name: CUTC_HUMAN

NCBI Description

Members of the CUT family of copper transporters are associated with copper homeostasis and are involved in the uptake, storage, delivery, and efflux of copper (Gupta et al., 1995 [PubMed 7635807]; Li et al., 2005 [PubMed 16182249]).[supplied by OMIM, Mar 2008]

Uniprot Description

CUTC: a copper binding protein associated with copper homeostasis and transport. Widely expressed in human tissues. Its nuclear and cytoplasmic distribution suggests that it may be a nucleocytoplasmic copper ion shuttle protein.

Protein type: Carrier

Chromosomal Location of Human Ortholog: 10q24.2

Cellular Component: nucleoplasm; cytoplasm; nucleolus; nucleus

Molecular Function: copper ion binding

Biological Process: copper ion transport; copper ion homeostasis; protein tetramerization