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Rabbit CUP Polyclonal Antibody | anti-CUP antibody

Rabbit anti-Drosophila melanogaster (Fruit fly) CUP Polyclonal Antibody

Gene Names
cup; CG11181; Cup; CUP; DmCup; DmelCG11181; fs(1)cup; fs(2)cup; i239
Reactivity
Drosophila melanogaster (Fruit fly)
Applications
ELISA, Western Blot
Purity
Protein A/G
Synonyms
CUP; Polyclonal Antibody; Rabbit anti-Drosophila melanogaster (Fruit fly) CUP Polyclonal Antibody; CUP Antibody; Protein cup; Oskar ribonucleoprotein complex 147kDa subunit; cup fs(2)cup CG11181; anti-CUP antibody
Ordering
Host
Rabbit
Reactivity
Drosophila melanogaster (Fruit fly)
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Protein A/G
Form/Format
Liquid
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH7.4
Applicable Applications for anti-CUP antibody
ELISA (EIA), WB (Western Blot) (ensure identification of antigen)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) cup protein
Conjugation
Non-conjugate
Modification
Unmodified
Deliverables
1. 200ug recombinant immunogen protein/peptide (positive control).
2. 1mL preimmune serum (negative control)
3. 10mg rabbit polyclonal antibody purified by Protein A/G.
Quality Guarantee
1. Antibody purity >90% confirmed by SDS-PAGE.
2. Antibody titer > 1: 64,000 confirmed by ELISA
3. Western Blot positive for the immunogen protein (Not applicable for synthetic peptide).
Complementary Antibody
Customer can choose 1 FREE antibody from the list below. Please specify the catalog # when order:
* 6*His Monoclonal Antibody #MBS1491670
* DYKDDDDK tag Monoclonal Antibody #MBS1493946
* GAPDH Monoclonal Antibody #MBS1495524
* GFP Monoclonal Antibody #MBS1496050
* Myc tag Monoclonal Antibody #MBS1497694
* GST Monoclonal Antibody #MBS1497871
* Sumo tag Monoclonal Antibody #MBS1498878
* Goat Anti-Rabbit IgG (H+L) Antibody; HRP conjugated #MBS7053510
* HA-Tag Monoclonal Antibody #MBS7135631
* E-Tag Monoclonal Antibody #MBS7135632
* TUBA1A Monoclonal Antibody #MBS7135645
* TUBB Monoclonal Antibody #MBS9018332
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
125,672 Da
NCBI Official Full Name
cup, isoform C
NCBI Official Symbol
cup
NCBI Official Synonym Symbols
CG11181; Cup; CUP; DmCup; DmelCG11181; fs(1)cup; fs(2)cup; i239
NCBI Protein Information
CG11181 gene product from transcript CG11181-RC
UniProt Protein Name
Protein cup
Protein Family
UniProt Gene Name
cup
UniProt Synonym Gene Names
fs(2)cup

Uniprot Description

Adapter protein that plays a central role in localization of transcripts in the oocyte and in young embryos (PubMed:9118812). Maintains RNA targets in a repressed state by promoting their deadenylation and protects deadenylated mRNAs from further degradation (PubMed:21937713). Binds to and recruits eIF-4E to the 3'-UTR of some mRNA targets which prevents interaction between eIF-4E and eIF4G (PubMed:14685270, PubMed:15465908, PubMed:21081899). This may contribute to translational repression but does not appear to be necessary for it to occur (PubMed:21081899). Can promote translational repression independently of deadenylation and eIF-4E binding (PubMed:21937713). Required for correct localization of eIF-4E in the developing oocyte (PubMed:15465908). Required for translational repression of oskar (osk) mRNA (PubMed:14691132, PubMed:14723848). Also required for the translational repression of nanos (nos) mRNA (PubMed:21081899). Promotes the accumulation of the germ plasm components osk, vas and stau at the posterior pole of the oocyte and is required for germ cell development (PubMed:22454519, PubMed:17277377). Represses orb positive autoregulatory activity which prevents premature activation of orb and ensures its accumulation specifically in the developing oocyte (PubMed:22164257).

Research Articles on CUP

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Product Notes

The CUP cup (Catalog #AAA9014969) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-Drosophila melanogaster (Fruit fly) CUP Polyclonal Antibody reacts with Drosophila melanogaster (Fruit fly) and may cross-react with other species as described in the data sheet. AAA Biotech's CUP can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), WB (Western Blot) (ensure identification of antigen). Researchers should empirically determine the suitability of the CUP cup for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CUP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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