Western Blot (WB)
(CTSL1 rabbit polyclonal antibody. Western Blot analysis of CTSL1 expression in mouse spleen.)
Rabbit anti-Human, Mouse CTSL1 Polyclonal Antibody | anti-CTSL1 antibody
CTSL1 (Cathepsin L1, Major Excreted Protein, MEP, Cathepsin L1 Heavy Chain, Cathepsin L1 Light Chain, CTSL) (AP)
Gene Names
CTSL1; MEP; CATL; CTSL; FLJ31037; CTSL1
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
CTSL1; Polyclonal Antibody; CTSL1 (Cathepsin L1; Major Excreted Protein; MEP; Cathepsin L1 Heavy Chain; Cathepsin L1 Light Chain; CTSL) (AP); anti-CTSL1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human CTSL1. Species Crossreactivity: mouse.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Applicable Applications for anti-CTSL1 antibody
Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Full length human CTSL1, aa1-333 (NP_001903.1).
Immunogen Sequence
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Conjugate
AP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(CTSL1 rabbit polyclonal antibody. Western Blot analysis of CTSL1 expression in mouse spleen.)
Western Blot (WB)
(CTSL1 rabbit polyclonal antibody. Western Blot analysis of CTSL1 expression in mouse spleen.)
Western Blot (WB)
(Western Blot analysis of CTSL1 expression in transfected 293T cell line by CTSL1 polyclonal antibody. Lane 1: CTSL1 transfected lysate (37.6kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of CTSL1 expression in transfected 293T cell line by CTSL1 polyclonal antibody. Lane 1: CTSL1 transfected lysate (37.6kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-CTSL1 antibody
CTSL1 is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor.
Product Categories/Family for anti-CTSL1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
cathepsin L1 preproprotein [Homo sapiens]
NCBI Official Synonym Full Names
cathepsin L1
NCBI Official Symbol
CTSL1
NCBI Official Synonym Symbols
MEP; CATL; CTSL; FLJ31037; CTSL1
UniProt Protein Name
Cathepsin L1
UniProt Gene Name
CTSL1
UniProt Synonym Gene Names
CTSL; MEP
UniProt Entry Name
CATL1_HUMAN
Uniprot Description
CTSL1: Important for the overall degradation of proteins in lysosomes. Belongs to the peptidase C1 family.
Protein type: Motility/polarity/chemotaxis; EC 3.4.22.15; Protease
Chromosomal Location of Human Ortholog: 9q21.33
Cellular Component: extracellular space; lysosomal lumen; lysosome; extracellular region; nucleus
Molecular Function: collagen binding; protein binding; proteoglycan binding; histone binding; fibronectin binding; cysteine-type endopeptidase activity; cysteine-type peptidase activity
Biological Process: antigen processing and presentation; extracellular matrix disassembly; collagen catabolic process; extracellular matrix organization and biogenesis; adaptive immune response; proteolysis involved in cellular protein catabolic process; toll-like receptor signaling pathway; innate immune response; antigen processing and presentation of exogenous peptide antigen via MHC class II; proteolysis
Similar Products
Product Notes
The CTSL1 ctsl1 (Catalog #AAA6375072) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CTSL1 (Cathepsin L1, Major Excreted Protein, MEP, Cathepsin L1 Heavy Chain, Cathepsin L1 Light Chain, CTSL) (AP) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CTSL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the CTSL1 ctsl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CTSL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
