Western Blot (WB)
(Western blot analysis of CTPS2 Antibody (N-term) in Hela cell line lysates (35ug/lane). CTPS2 (arrow) was detected using the purified Pab.)
Rabbit anti-Human CTPS2 Polyclonal Antibody | anti-CTPS2 antibody
CTPS2, NT (CTP Synthetase 2, UTP-ammonia Ligase 2, CTP Synthase 2) (APC)
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Western Blot (WB)
(Western blot analysis of CTPS2 Antibody (N-term) in Hela cell line lysates (35ug/lane). CTPS2 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of CTPS2 Antibody (N-term) in Hela cell line lysates (35ug/lane). CTPS2 (arrow) was detected using the purified Pab.)
Flow Cytometry (FC/FACS)
(CTPS2 Antibody (N-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(CTPS2 Antibody (N-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Three alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq]
Uniprot Description
CTPS2: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides. Belongs to the CTP synthase family.
Protein type: EC 6.3.4.2; Ligase; Nucleotide Metabolism - pyrimidine
Chromosomal Location of Human Ortholog: Xp22
Cellular Component: mitochondrion; cytosol
Molecular Function: CTP synthase activity; ATP binding
Biological Process: pyrimidine nucleotide metabolic process; nucleobase, nucleoside and nucleotide metabolic process; nucleobase, nucleoside and nucleotide interconversion; glutamine metabolic process
Research Articles on CTPS2
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Product Notes
The CTPS2 ctps2 (Catalog #AAA6470822) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CTPS2, NT (CTP Synthetase 2, UTP-ammonia Ligase 2, CTP Synthase 2) (APC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CTPS2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-1:500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the CTPS2 ctps2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CTPS2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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