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Western Blot (WB) (Western Blot analysis of HuvEc cells using CTPS Polyclonal Antibody)

Rabbit CTPS Polyclonal Antibody | anti-CTPS antibody

CTPS Polyclonal Antibody

Gene Names
CTPS1; CTPS; IMD24
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
CTPS; Polyclonal Antibody; CTPS Polyclonal Antibody; CTPS1; CTP synthase 1; CTP synthetase 1; UTP--ammonia ligase 1; anti-CTPS antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
CTPS Polyclonal Antibody detects endogenous levels of CTPS protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
435
Applicable Applications for anti-CTPS antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
Western Blot: 1:500 - 1:2000
Immunohistochemistry: 1:100 - 1:300
ELISA: 1:10000
Not yet tested in other applications.
Immunogen Type
peptide
Immunogen Description
Synthesized peptide derived from the N-terminal region of human CTPS.
Target Name
CTPS
Preparation and Storage
Store at -20 degree C/1 year

Western Blot (WB)

(Western Blot analysis of HuvEc cells using CTPS Polyclonal Antibody)

Western Blot (WB) (Western Blot analysis of HuvEc cells using CTPS Polyclonal Antibody)

Western Blot (WB)

(Western Blot analysis of NIH-3T3 K562 cells using CTPS Polyclonal Antibody)

Western Blot (WB) (Western Blot analysis of NIH-3T3 K562 cells using CTPS Polyclonal Antibody)
Product Categories/Family for anti-CTPS antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41,220 Da
NCBI Official Full Name
CTP synthase 1 isoform b
NCBI Official Synonym Full Names
CTP synthase 1
NCBI Official Symbol
CTPS1
NCBI Official Synonym Symbols
CTPS; IMD24
NCBI Protein Information
CTP synthase 1
UniProt Protein Name
CTP synthase 1
UniProt Gene Name
CTPS1
UniProt Entry Name
PYRG1_HUMAN

NCBI Description

This gene encodes an enzyme responsible for the catalytic conversion of UTP (uridine triphosphate) to CTP (cytidine triphospate). This reaction is an important step in the biosynthesis of phospholipids and nucleic acids. Activity of this proten is important in the immune system, and loss of function of this gene has been associated with immunodeficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Uniprot Description

CTPS: the enzyme cytidine-5-prime-triphosphate synthetase converts UTP to CTP. Important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis. The region to which the CTPS gene has been mapped is the location of breakpoints involved in several tumor types.

Protein type: Nucleotide Metabolism - pyrimidine; Motility/polarity/chemotaxis; Ligase; EC 6.3.4.2

Chromosomal Location of Human Ortholog: 1p34.1

Cellular Component: membrane; cytosol

Molecular Function: CTP synthase activity; ATP binding

Biological Process: B cell proliferation; response to drug; T cell proliferation; CTP biosynthetic process; nucleobase, nucleoside and nucleotide metabolic process; nucleobase, nucleoside and nucleotide interconversion; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; glutamine metabolic process

Disease: Immunodeficiency 24

Research Articles on CTPS

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Product Notes

The CTPS ctps1 (Catalog #AAA9404872) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CTPS Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CTPS can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). Western Blot: 1:500 - 1:2000 Immunohistochemistry: 1:100 - 1:300 ELISA: 1:10000 Not yet tested in other applications. Researchers should empirically determine the suitability of the CTPS ctps1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CTPS, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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