Rabbit anti-Mouse Ctgf Polyclonal Antibody | anti-Ctgf antibody

Ctgf Antibody

Cat. Num. AAA7051885

• Gene Names: Ctgf; Ccn2; Hcs24; Fisp12; fisp-12
• Reactivity: Mouse
• Applications: ELISA
• Purity: >95%, Protein G purified
• Synonyms: Ctgf; Polyclonal Antibody; Ctgf Antibody; Connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Protein FISP-12; Ccn2; Fisp-12; Fisp12; Hcs24; anti-Ctgf antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G purified
• Form/Format: Liquid
• Sequence Length: 348

• Applicable Applications for anti-Ctgf antibody: ELISA (EIA)
• Immunogen: Recombinant Mouse Connective tissue growth factor protein (26-344AA)
• Conjugation: Non-conjugated
• Preservative: 0.03% Proclin 300
• Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western BlotPositive WB detected in: Rat skeletal muscle tissueAll lanes: Ctgf antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 38 KDaObserved band size: 38 KDa)

Related Product Information for anti-Ctgf antibody

Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes (By similarity). Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells (By similarity). Enhances fibroblast growth factor-induced DNA synthesis (By similarity).

NCBI and Uniprot Product Information

• NCBI GI #: 171846283
• NCBI GeneID: 14219
• NCBI Accession #: NP_034347.2
• NCBI GenBank Nucleotide #: NM_010217.2
• UniProt Accession #: P29268; Q922U0; G5E830
• Molecular Weight: 37,824 Da
• NCBI Official Full Name: connective tissue growth factor
• NCBI Official Synonym Full Names: connective tissue growth factor
• NCBI Official Symbol: Ctgf
• NCBI Official Synonym Symbols: Ccn2; Hcs24; Fisp12; fisp-12
• NCBI Protein Information: connective tissue growth factor
• UniProt Protein Name: Connective tissue growth factor
• Protein Family: Connective tissue growth factor
• UniProt Gene Name: Ctgf
• UniProt Synonym Gene Names: Ccn2; Fisp-12; Fisp12; Hcs24

Uniprot Description

CTGF: Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Belongs to the CCN family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 10 A4|10 11.84 cM

Cellular Component: cell cortex; cis-Golgi network; cytosol; extracellular region; extracellular space; Golgi apparatus; intracellular membrane-bound organelle; perinuclear region of cytoplasm; proteinaceous extracellular matrix

Molecular Function: fibronectin binding; growth factor activity; heparin binding; integrin binding; protein C-terminus binding

Biological Process: angiogenesis; cartilage condensation; cell differentiation; cell migration; cell-cell signaling; cell-matrix adhesion; fibroblast growth factor receptor signaling pathway; integrin-mediated signaling pathway; lung development; ossification; positive regulation of caspase activity; positive regulation of cell activation; positive regulation of cell differentiation; positive regulation of cell proliferation; positive regulation of collagen biosynthetic process; positive regulation of JNK cascade; positive regulation of protein amino acid phosphorylation; positive regulation of stress fiber formation; regulation of chondrocyte differentiation; tissue homeostasis