Western Blot (WB)
(Western blot analysis of anti-CTDSP2 Antibody (N-term) in mouse lung tissue lysates (35ug/lane). CTDSP2(arrow) was detected using the purified Pab.)
Rabbit anti-Human, Mouse CTDSP2 Polyclonal Antibody | anti-CTDSP2 antibody
CTDSP2, NT (Small CTD Phosphatase 2, Carboxy-terminal Domain RNA Polymerase II Polypeptide A Small Phosphatase 2, Small C-terminal Domain Phosphatase 2, SCP2, Nuclear LIM Interactor-interacting Factor 2, NLI-interacting Factor 2, Protein OS-4, NIF2, OS4,
Purified by ammonium sulfate precipitation.
Purified by ammonium sulfate precipitation.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:250
Immunohistochemistry: 1:50-1:100
Western Blot (WB)
(Western blot analysis of anti-CTDSP2 Antibody (N-term) in mouse lung tissue lysates (35ug/lane). CTDSP2(arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of anti-CTDSP2 Antibody (N-term) in mouse lung tissue lysates (35ug/lane). CTDSP2(arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of anti-CTDSP2 Antibody (N-term) in HepG2 cell line lysates (35ug/lane). hCTDSP2-S27(arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of anti-CTDSP2 Antibody (N-term) in HepG2 cell line lysates (35ug/lane). hCTDSP2-S27(arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with CTDSP2 Antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with CTDSP2 Antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
Uniprot Description
CTDSP2: Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.
Protein type: Phosphatase; EC 3.1.3.16; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 12q14.1
Cellular Component: nucleoplasm
Molecular Function: protein binding; metal ion binding; CTD phosphatase activity
Biological Process: unfolded protein response, activation of signaling protein activity; cellular protein metabolic process; negative regulation of protein amino acid phosphorylation; unfolded protein response; protein amino acid dephosphorylation
Research Articles on CTDSP2
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Product Notes
The CTDSP2 ctdsp2 (Catalog #AAA631069) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CTDSP2, NT (Small CTD Phosphatase 2, Carboxy-terminal Domain RNA Polymerase II Polypeptide A Small Phosphatase 2, Small C-terminal Domain Phosphatase 2, SCP2, Nuclear LIM Interactor-interacting Factor 2, NLI-interacting Factor 2, Protein OS-4, NIF2, OS4, reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CTDSP2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Dilution: ELISA: 1:1,000 Western Blot: 1:100-1:250 Immunohistochemistry: 1:50-1:100. Researchers should empirically determine the suitability of the CTDSP2 ctdsp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CTDSP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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