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Western Blot (WB) (CTAG2 Antibody (Center) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the CTAG2 antibody detected the CTAG2 protein (arrow).)

Rabbit anti-Human CTAG2 Polyclonal Antibody | anti-CTAG2 antibody

CTAG2 Antibody (Center)

Gene Names
CTAG2; CT2; ESO2; CAMEL; CT6.2; CT6.2a; CT6.2b; LAGE-1; LAGE2B
Reactivity
Human
Applications
Western Blot, ELISA, Immunohistochemistry
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
CTAG2; Polyclonal Antibody; CTAG2 Antibody (Center); Cancer/testis antigen 2; CT2; Autoimmunogenic cancer/testis antigen NY-ESO-2; Cancer/testis antigen 62; CT62; L antigen family member 1; LAGE-1; ESO2; LAGE1; anti-CTAG2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This CTAG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-149 amino acids from the Central region of human CTAG2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.3 (varies by lot)
Sequence Positions
122-149
Sequence Length
180
Applicable Applications for anti-CTAG2 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(CTAG2 Antibody (Center) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the CTAG2 antibody detected the CTAG2 protein (arrow).)

Western Blot (WB) (CTAG2 Antibody (Center) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the CTAG2 antibody detected the CTAG2 protein (arrow).)

Immunohistochemistry (IHC)

(CTAG2 Antibody (Center) (MBS9203138)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CTAG2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (CTAG2 Antibody (Center) (MBS9203138)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CTAG2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-CTAG2 antibody
This gene encodes an autoimmunogenic tumor antigen that
belongs to the ESO/LAGE family of cancer-testis antigens. This
protein is expressed in a wide array of cancers including melanoma,
breast cancer, bladder cancer and prostate cancer. This protein is
also expressed in normal testis tissue. An alternative open reading
frame product of this gene has been described in PMID 10399963.
This alternate protein, termed CAMEL, is a tumor antigen that is
recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate
splicing results in multiple transcript variants. [provided by
RefSeq].
Product Categories/Family for anti-CTAG2 antibody
References
Wang, X.Y., et al. Oncol. Rep. 21(3):713-719(2009)
Shao, Y., et al. J. Cancer Res. Clin. Oncol. 134(4):495-502(2008)
Andrade, V.C., et al. Cancer Immun. 8, 2 (2008) :
Kan, T., et al. Oncology 70(1):25-33(2006)
Scanlan, M.J., et al. Immunol. Rev. 188, 22-32 (2002) :

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
21061
NCBI Official Full Name
cancer/testis antigen 2 isoform LAGE-1b
NCBI Official Synonym Full Names
cancer/testis antigen 2
NCBI Official Symbol
CTAG2
NCBI Official Synonym Symbols
CT2; ESO2; CAMEL; CT6.2; CT6.2a; CT6.2b; LAGE-1; LAGE2B
NCBI Protein Information
cancer/testis antigen 2
UniProt Protein Name
Cancer/testis antigen 2
Protein Family
UniProt Gene Name
CTAG2
UniProt Synonym Gene Names
ESO2; LAGE1; CT2; CT6.2; LAGE-1
UniProt Entry Name
CTAG2_HUMAN

NCBI Description

This gene encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID:10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Uniprot Description

CTAG2: an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID 10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

Protein type: Cancer Testis Antigen (CTA); Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: centrosome

Research Articles on CTAG2

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Product Notes

The CTAG2 ctag2 (Catalog #AAA9203138) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 122-149. The CTAG2 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CTAG2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the CTAG2 ctag2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CTAG2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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