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Immunohistochemistry (IHC) (CSAD Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CSAD Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Rabbit anti-Human CSAD Polyclonal Antibody | anti-CSAD antibody

CSAD Antibody (Center)

Gene Names
CSAD; CSD; PCAP
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
CSAD; Polyclonal Antibody; CSAD Antibody (Center); Cysteine sulfinic acid decarboxylase; Cysteine-sulfinate decarboxylase; Sulfinoalanine decarboxylase; CSD; anti-CSAD antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This CSAD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-226 amino acids from the Central region of human CSAD.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
197-226
Sequence Length
520
Applicable Applications for anti-CSAD antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
IHC~~1:50~100
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Immunohistochemistry (IHC)

(CSAD Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CSAD Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (CSAD Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CSAD Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Western Blot (WB)

(CSAD Antibody (Center) western blot analysis in CEM,A549 cell line lysates (35ug/lane).This demonstrates the CSAD antibody detected the CSAD protein (arrow).)

Western Blot (WB) (CSAD Antibody (Center) western blot analysis in CEM,A549 cell line lysates (35ug/lane).This demonstrates the CSAD antibody detected the CSAD protein (arrow).)
Related Product Information for anti-CSAD antibody
Cysteine sulfinic acid decarboxylase (CSAD) catalyses the penultimate and rate limiting step of taurine synthesis. Taurine is an amino sulphonic acid and is one of the most abundant amino acids in the brain. It has been found to be essential to a number of biological processes such as development of the brain and eye, reproduction, diabetes, osmoregulation as well as the anti-inflammatory activity of leukocytes.
Product Categories/Family for anti-CSAD antibody
References
Park, E., et al. Biochim. Biophys. Acta 1574(3):403-406(2002)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
55023
NCBI Official Full Name
cysteine sulfinic acid decarboxylase isoform 2
NCBI Official Synonym Full Names
cysteine sulfinic acid decarboxylase
NCBI Official Symbol
CSAD
NCBI Official Synonym Symbols
CSD; PCAP
NCBI Protein Information
cysteine sulfinic acid decarboxylase
UniProt Protein Name
Cysteine sulfinic acid decarboxylase
UniProt Gene Name
CSAD
UniProt Synonym Gene Names
CSD
UniProt Entry Name
CSAD_HUMAN

NCBI Description

This gene encodes a member of the group 2 decarboxylase family. A similar protein in rodents plays a role in multiple biological processes as the rate-limiting enzyme in taurine biosynthesis, catalyzing the decarboxylation of cysteinesulfinate to hypotaurine. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

Uniprot Description

CSAD: a member of the group 2 decarboxylase family. A similar protein in rodents plays a role in multiple biological processes as the rate-limiting enzyme in taurine biosynthesis, catalyzing the decarboxylation of cysteinesulfinate to hypotaurine. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

Protein type: Other Amino Acids Metabolism - taurine and hypotaurine; EC 4.1.1.29; Lyase

Chromosomal Location of Human Ortholog: 12q13.11-q14.3

Molecular Function: sulfinoalanine decarboxylase activity; pyridoxal phosphate binding

Biological Process: sulfur amino acid metabolic process; sulfur amino acid catabolic process; taurine biosynthetic process

Research Articles on CSAD

Similar Products

Product Notes

The CSAD csad (Catalog #AAA9214387) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 197-226. The CSAD Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CSAD can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB). IHC~~1:50~100 WB~~1:1000. Researchers should empirically determine the suitability of the CSAD csad for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CSAD, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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