Rabbit anti-Mouse Cryptochrome 1 Polyclonal Antibody | anti-siu50817b antibody

Cryptochrome 1 (CRY1)

Cat. Num. AAA616247

• Reactivity: Mouse
• Applications: ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: Cryptochrome 1; Polyclonal Antibody; Cryptochrome 1 (CRY1); Anti -Cryptochrome 1 (CRY1); anti-siu50817b antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes mouse Cryptochrome 1 (CRY1). No significant homology with CRY2.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a lyophilized powder from PBS, pH 7.4, 0.1% BSA. Reconstitute with 100ul of sterile PBS.

• Applicable Applications for anti-siu50817b antibody: ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in Western Blot, ELISA, Immunohistochemistry and Immunoprecipitation.; Dilution: Western Blot: 1-10ug/ml. Using ECL.; ELISA: 1:10,000-1:100,000 using 50-100ng of C7942-38/well.; Immunohistochemistry: 2-10ug/ml in 4% PF-fixed and in frozen free floating sections.
• Immunogen: Synthetic peptide corresponding to the 21aa sequence near the C-terminus of mouse CRY1 conjuated to KLH. Species Sequence Homology: monkey and human; 85%, chicken; 76%, frog;, 71%
• Preparation and Storage: Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Related Product Information for anti-siu50817b antibody

Circadian rhythm is one of the most fascinating and complex biological phenomenon's. The circadian clock controls biological activities on daily light-dark cycles in species from cyanobacteria to humans. The circadian clock has three major components: A photoactive pigment (chromophore) for sensing light and transmitting light signals, the circadian clock that oscillates every ~24-hrs, and the genes controlled by the circadian clock to bring about the physiological and behavioral changes. Several genes (Drosophila Clock Per, Tim; mammalian Per1, Per2, Per3, MOP3 and MOP4, and BMAL1) have been linked to rhythmicity or circadian behavior of living organisms. However, very little is known about the mammalian photosensory molecules. Most recently mammalian homolog of the plant blue-light photoreceptors termed cryptochromes have been identified. Mouse CRY1 and CRY2, are 606aa and 569aa protein, respectively. Cry1 and Cry are specifically expressed in ganglion cell and inner nuclear layers of the mouse retina. CRY1 is expressed at high level in the SCN and oscillates in a circadian manner. Like other genes implicated in circadian mechanism, CRY1 and CRY2 are also expressed in most animal tissues. Therefore, mammalian cryptochromes appears to play an important role in entrainment of the circadian clock.

Product Categories/Family for anti-siu50817b antibody

Antibodies; Abs to Receptors

NCBI and Uniprot Product Information

• NCBI GI #: 293337104
• NCBI GeneID: 100384475
• NCBI Accession #: NP_001170477.1
• NCBI GenBank Nucleotide #: NM_001177006.1
• NCBI Official Full Name: LOC100384475
• NCBI Official Synonym Full Names: LOC100384475
• NCBI Official Symbol: siu50817b
• NCBI Protein Information: LOC100384475; cryptochrome 1