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Western Blot (WB) (CRLS1 Antibody (C-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the CRLS1 antibody detected the CRLS1 protein (arrow).)

Rabbit CRLS1 Polyclonal Antibody | anti-CRLS1 antibody

CRLS1 Antibody (C-term)

Gene Names
CRLS1; CLS; CLS1; GCD10; C20orf155; dJ967N21.6
Reactivity
Human (Predicted Reactivity: Mouse, Rat)
Applications
Western Blot, ELISA, Immunohistochemistry
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
CRLS1; Polyclonal Antibody; CRLS1 Antibody (C-term); Cardiolipin synthase; CLS; 278-; Protein GCD10 homolog; C20orf155; CLS1; anti-CRLS1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse, Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This CRLS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the C-terminal region of human CRLS1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
198-226
Sequence Length
202
Applicable Applications for anti-CRLS1 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(CRLS1 Antibody (C-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the CRLS1 antibody detected the CRLS1 protein (arrow).)

Western Blot (WB) (CRLS1 Antibody (C-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the CRLS1 antibody detected the CRLS1 protein (arrow).)

Immunohistochemistry (IHC)

(CRLS1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CRLS1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (CRLS1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CRLS1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Product Categories/Family for anti-CRLS1 antibody
References
Garcia-Carrasco, M., et al. Clin Rev Allergy Immunol 36 (2-3), 104-108 (2009) :
Lee, J.L., et al. Clin Rev Allergy Immunol 36 (2-3), 126-130 (2009) :
Stojanovich, L., et al. Clin Rev Allergy Immunol 36 (2-3), 74-79 (2009) :
Miesbach, W. Clin Rev Allergy Immunol 36 (2-3), 91-97 (2009) :
Chen, D., et al. Biochem. J. 398(2):169-176(2006)
Lu, B., et al. J. Lipid Res. 47(6):1140-1145(2006)
Houtkooper, R.H., et al. FEBS Lett. 580(13):3059-3064(2006)
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Johnson, E.M., et al. Nucleic Acids Res. 31(11):2915-2925(2003)
Deloukas, P., et al. Nature 414(6866):865-871(2001)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
32593
NCBI Official Full Name
cardiolipin synthase (CMP-forming) isoform 2
NCBI Official Synonym Full Names
cardiolipin synthase 1
NCBI Official Symbol
CRLS1
NCBI Official Synonym Symbols
CLS; CLS1; GCD10; C20orf155; dJ967N21.6
NCBI Protein Information
cardiolipin synthase (CMP-forming)
UniProt Protein Name
Cardiolipin synthase (CMP-forming)
UniProt Gene Name
CRLS1
UniProt Synonym Gene Names
C20orf155; CLS1; CLS
UniProt Entry Name
CRLS1_HUMAN

Uniprot Description

CRLS1: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Belongs to the CDP-alcohol phosphatidyltransferase class-I family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Lipid Metabolism - glycerophospholipid; Transferase; Membrane protein, integral; EC 2.7.8.-; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 20p13-p12.3

Cellular Component: mitochondrial inner membrane; integral to membrane

Molecular Function: phosphotransferase activity, for other substituted phosphate groups

Biological Process: cardiolipin biosynthetic process; phospholipid metabolic process; glycerophospholipid biosynthetic process

Research Articles on CRLS1

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Product Notes

The CRLS1 crls1 (Catalog #AAA9200914) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 198-226. The CRLS1 Antibody (C-term) reacts with Human (Predicted Reactivity: Mouse, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's CRLS1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the CRLS1 crls1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CRLS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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