Rabbit anti-Human CRIPTO Polyclonal Antibody | anti-oep antibody
CRIPTO, CT (Teratocarcinoma-derived Growth Factor 1, Epidermal Growth Factor-like Cripto Protein CR1, Cripto-1 Growth Factor, CRGF, TDGF1)
Gene Names
oep; cb85; tdgf1; cripto; wu:fe01d04; zgc:109829
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
CRIPTO; Polyclonal Antibody; CT (Teratocarcinoma-derived Growth Factor 1; Epidermal Growth Factor-like Cripto Protein CR1; Cripto-1 Growth Factor; CRGF; TDGF1); Anti -CRIPTO; anti-oep antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human TDGF1.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Applicable Applications for anti-oep antibody
ELISA (EL/EIA), Immunohistochemistry (IHC)
Application Notes
Suitable for use in ELISA and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Immunohistochemistry: 1:10-1:50
Dilution: ELISA: 1:1,000
Immunohistochemistry: 1:10-1:50
Immunogen
Synthetic peptide selected from the C-terminal region of human TDGF1 (KLH).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-oep antibody
The human cDNA for CRIPTO (TDGF1), isolated from a teratocarcinoma cell line, encodes a protein of 188aa. The central section has structural similarities with the human transforming growth factor alpha and epidermal growth factor (EGF). CRIPTO transcripts are detected only in undifferentiated cells and disappear after cell differentiation induced by retinoic acid treatment. The EGF-CFC (Cripto, Frl1, and Cryptic) gene family has an important role in vertebrate development. Cripto is required for germ-layer formation and the correct positioning of the anterior-posterior axis in mic; Cryptic (CFC1) is necessary for assignment of the left-right axis. Prior to gastrulation, Cripto expression is initially symmetric and uniform in the epiblast, and then becomes asymmetric in a proximal-distal gradient. Cripto gene when rendered inactive is fatal in the murine model. Cripto and Cryptic are essential cofactors for Nodal family proteins, which transduce signals for mesoderm development. Cryptic protein is required for appropriate symmetry development in humans. TDGF1, like CFC1, is an EGF-CFC family member and required coreceptor in NODAL signaling, a developmental program implicated in midline, forebrain, and left-right axis development in model organisms. A mutation in the conserved CFC domain of the TDGF1 gene has been identified in a patient with midline anomalies of the forebrain. The mutant protein was inactive in a zebrafish rescue assay.
Product Categories/Family for anti-oep antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
cryptic protein
NCBI Official Synonym Full Names
one-eyed pinhead
NCBI Official Symbol
oep
NCBI Official Synonym Symbols
cb85; tdgf1; cripto; wu:fe01d04; zgc:109829
NCBI Protein Information
cryptic protein; one eyed pinhead; teratocarcinoma-derived growth factor 1
Research Articles on oep
Similar Products
Product Notes
The oep (Catalog #AAA624351) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CRIPTO, CT (Teratocarcinoma-derived Growth Factor 1, Epidermal Growth Factor-like Cripto Protein CR1, Cripto-1 Growth Factor, CRGF, TDGF1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CRIPTO can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Immunohistochemistry (IHC). Suitable for use in ELISA and Immunohistochemistry. Dilution: ELISA: 1:1,000 Immunohistochemistry: 1:10-1:50. Researchers should empirically determine the suitability of the oep for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CRIPTO, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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