Rabbit anti-Human CREB1 Polyclonal Antibody | anti-CREB1 antibody

CREB1 Polyclonal Antibody

Cat. Num. AAA2556120

• Gene Names: CREB1; CREB; CREB-1
• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Affinity Purification
• Synonyms: CREB1; Polyclonal Antibody; CREB1 Polyclonal Antibody; Active transcription factor CREB; cAMP response element binding protein 1; cAMP response element binding protein; cAMP responsive element binding protein 1; cAMP-responsive element-binding protein 1; CREB; CREB-1; Cyclic AMP-responsive element-binding protein 1; MGC9284; OTTHUMP00000163864; OTTHUMP00000163865; OTTHUMP00000206660; OTTHUMP00000206662; OTTHUMP00000206667; Transactivator protein; anti-CREB1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity Purification
• Form/Format: PBS with 0.02% sodium azide, 100 mug/ml BSA and 50% glycerol.
• Concentration: 400 mug/mL (varies by lot)
• Sequence Length: 327

• Applicable Applications for anti-CREB1 antibody: Immunohistochemistry (IHC)
• Application Notes: IHC: 1:200-1:800
• Immunogen: KLH conjugated synthetic peptide corresponding to Mouse CREB1
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human lung cancer using CREB1 Polyclonal Antibody at dilution of 1:200.)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human liver cancer using CREB1 Polyclonal Antibody at dilution of 1:200.)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human kidney using CREB1 Polyclonal Antibody at dilution of 1:200.)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human stomach cancer using CREB1 Polyclonal Antibody at dilution of 1:200.)

Related Product Information for anti-CREB1 antibody

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.

Product Categories/Family for anti-CREB1 antibody

Cancer; Epigenetics and Nuclear Signaling; Immunology

NCBI and Uniprot Product Information

• NCBI GI #: 4758054
• NCBI GeneID: 1385
• NCBI Accession #: NP_004370.1
• NCBI GenBank Nucleotide #: NM_004379.5
• UniProt Accession #: P16220; P21934; Q6V963; Q9UMA7
• Molecular Weight: 35,136 Da
• NCBI Official Full Name: cyclic AMP-responsive element-binding protein 1 isoform A
• NCBI Official Synonym Full Names: cAMP responsive element binding protein 1
• NCBI Official Symbol: CREB1
• NCBI Official Synonym Symbols: CREB; CREB-1
• NCBI Protein Information: cyclic AMP-responsive element-binding protein 1
• UniProt Protein Name: Cyclic AMP-responsive element-binding protein 1
• Protein Family: Cyclic AMP-responsive element-binding protein
• UniProt Gene Name: CREB1
• UniProt Synonym Gene Names: CREB-1; cAMP-responsive element-binding protein 1

NCBI Description

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]

Uniprot Description

Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.