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Western Blot (WB) (CRB3 Antibody (Center) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the CRB3 antibody detected the CRB3 protein (arrow).)

Rabbit anti-Human, Mouse CRB3 Polyclonal Antibody | anti-CRB3 antibody

CRB3, ID (CRB3, Crumbs protein homolog 3)

Reactivity
Human, Mouse
Applications
ELISA, Western Blot
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Synonyms
CRB3; Polyclonal Antibody; ID (CRB3; Crumbs protein homolog 3); Anti -CRB3; anti-CRB3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Human, mouse
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Applicable Applications for anti-CRB3 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunogen
CRB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-95 amino acids from the Central region of human CRB3.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(CRB3 Antibody (Center) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the CRB3 antibody detected the CRB3 protein (arrow).)

Western Blot (WB) (CRB3 Antibody (Center) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the CRB3 antibody detected the CRB3 protein (arrow).)
Related Product Information for anti-CRB3 antibody
This gene encodes a member of the Crumbs family of proteins. This protein may play a role in epithelial cell polarity and is associated with tight junctions at the apical surface of epithelial cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].
Product Categories/Family for anti-CRB3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
12,854 Da
NCBI Official Full Name
CRB3
NCBI Official Synonym Full Names
crumbs homolog 3 (Drosophila)
NCBI Official Symbol
CRB3
NCBI Protein Information
protein crumbs homolog 3; crumbs protein homolog 3
UniProt Protein Name
Protein crumbs homolog 3
Protein Family
UniProt Gene Name
CRB3
UniProt Entry Name
CRUM3_HUMAN

NCBI Description

This gene encodes a member of the Crumbs family of proteins. This protein may play a role in epithelial cell polarity and is associated with tight junctions at the apical surface of epithelial cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Uniprot Description

CRB3: Involved in the establishment of cell polarity in mammalian epithelial cells. Regulates the morphogenesis of tight junctions. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: tight junction; protein complex; apical plasma membrane; plasma membrane; integral to membrane; cell junction

Molecular Function: protein domain specific binding; SH3 domain binding

Biological Process: intercellular junction assembly and maintenance

Research Articles on CRB3

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Product Notes

The CRB3 crb3 (Catalog #AAA6006276) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CRB3, ID (CRB3, Crumbs protein homolog 3) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CRB3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the CRB3 crb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CRB3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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