Western Blot (WB)
(Western blot analysis of CPA4 using 293 whole cell lysates)
Rabbit anti-Human, Mouse CPA4 Polyclonal Antibody | anti-CPA4 antibody
CPA4 Antibody
Gene Names
CPA4; CPA3
Reactivity
Human, Mouse
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
CPA4; Polyclonal Antibody; CPA4 Antibody; Carboxypeptidase A3; Carboxypeptidase A4; CBPA4_HUMAN; CPA3; Cpa4; anti-CPA4 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
CPA4 antibody detects endogenous levels of total CPA4
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
388
Applicable Applications for anti-CPA4 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human CPA4
Subcellular Location
Secreted.
Tissue Specificity
Fetal expression in the adrenal gland, brain, heart, intestine, kidney, liver and lung. Except for fetal brain that shows no imprinting, expression was found preferentially from the maternal allele.
Predicted Cross Reactivity
Rabbit
Similarity
Rabbit (82%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of CPA4 using 293 whole cell lysates)
Western Blot (WB)
(Western blot analysis of CPA4 using 293 whole cell lysates)
Western Blot (WB)
(Western blot analysis of extracts from Hepg2, using CPA4 Antibody. Lane 1 was treated with the blocking peptide.)
Western Blot (WB)
(Western blot analysis of extracts from Hepg2, using CPA4 Antibody. Lane 1 was treated with the blocking peptide.)
Related Product Information for anti-CPA4 antibody
Function: Metalloprotease that could be involved in the histone hyperacetylation pathway (PubMed:10383164). Releases a C-terminal amino acid, with preference for-Phe, -Leu, -Ile, -Met, -Tyr and-Val (PubMed:20385563).
Subunit Structure: Monomer. Interacts with LXN.
Similarity: Belongs to the peptidase M14 family.
Subunit Structure: Monomer. Interacts with LXN.
Similarity: Belongs to the peptidase M14 family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 47 kDa
Predicted: 48 kDa
Predicted: 48 kDa
NCBI Official Full Name
carboxypeptidase A4 isoform 2
NCBI Official Synonym Full Names
carboxypeptidase A4
NCBI Official Symbol
CPA4
NCBI Official Synonym Symbols
CPA3
NCBI Protein Information
carboxypeptidase A4
UniProt Protein Name
Carboxypeptidase A4
Protein Family
UniProt Gene Name
CPA4
UniProt Synonym Gene Names
CPA3
NCBI Description
This gene is a member of the carboxypeptidase A/B subfamily, and it is located in a cluster with three other family members on chromosome 7. Carboxypeptidases are zinc-containing exopeptidases that catalyze the release of carboxy-terminal amino acids, and are synthesized as zymogens that are activated by proteolytic cleavage. This gene could be involved in the histone hyperacetylation pathway. It is imprinted and may be a strong candidate gene for prostate cancer aggressiveness. [provided by RefSeq, Jul 2008]
Uniprot Description
Metalloprotease that could be involved in the histone hyperacetylation pathway (PubMed:10383164). Releases a C-terminal amino acid, with preference for -Phe, -Leu, -Ile, -Met, -Tyr and -Val (PubMed:20385563).
Research Articles on CPA4
Similar Products
Product Notes
The CPA4 cpa4 (Catalog #AAA9609653) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CPA4 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CPA4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the CPA4 cpa4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CPA4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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