Immunohistochemistry - Paraffin (IHC)
(Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit anti-Human CPA1 / Carboxypeptidase A Polyclonal Antibody | anti-CPA1 antibody
Anti-CPA1 / Carboxypeptidase A Antibody (aa301-350) IHC-plus
Gene Names
CPA1; CPA
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Immunoaffinity purified
Synonyms
CPA1 / Carboxypeptidase A; Polyclonal Antibody; Anti-CPA1 / Carboxypeptidase A Antibody (aa301-350) IHC-plus; Rabbit Polyclonal (IgG) to Human CPA1 / Carboxypeptidase A; Human CPA1 / Carboxypeptidase A; CPA; Carboxypeptidase A1; Pancreatic carboxypeptidase A; Carboxypeptidase A; anti-CPA1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Carboxypeptidase A1 Antibody detects endogenous levels of Carboxypeptidase A1.
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
419
Applicable Applications for anti-CPA1 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA)
Application Notes
ELISA (1:10000)
IHC-P (10 ug/ml)
WB (1:500 - 1:1000)
IHC-P (10 ug/ml)
WB (1:500 - 1:1000)
Immunogen
CPA1 / Carboxypeptidase A antibody was raised against synthetic peptide derived from human Carboxypeptidase A1 (aa301-350).
Immunogen Description
Synthetic peptide derived from human Carboxypeptidase A1 (aa301-350).
Immunogen Type
Synthetic peptide
Antigen Modification
aa301-350
Target Species
Human
Preparation and Storage
Store at -20 degree C.
Immunohistochemistry - Paraffin (IHC)
(Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry - Paraffin (IHC)
(Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE))
Related Product Information for anti-CPA1 antibody
CPA1 Antibody, CPA Antibody, Carboxypeptidase A1 Antibody, Pancreatic carboxypeptidase A Antibody, Carboxypeptidase A Antibody Description: CPA1 / Carboxypeptidase A is a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
47,140 Da
NCBI Official Full Name
carboxypeptidase A1 preproprotein
NCBI Official Synonym Full Names
carboxypeptidase A1
NCBI Official Symbol
CPA1
NCBI Official Synonym Symbols
CPA
NCBI Protein Information
carboxypeptidase A1
UniProt Protein Name
Carboxypeptidase A1
Protein Family
UniProt Gene Name
CPA1
UniProt Synonym Gene Names
CPA
UniProt Entry Name
CBPA1_HUMAN
NCBI Description
This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer. [provided by RefSeq, Jan 2015]
Uniprot Description
CPA1: Carboxypeptidase that catalyzes the release of a C- terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro. Belongs to the peptidase M14 family.
Protein type: Secreted, signal peptide; EC 3.4.17.1; Protease; Secreted
Chromosomal Location of Human Ortholog: 7q32
Cellular Component: extracellular space
Molecular Function: metallocarboxypeptidase activity; zinc ion binding
Biological Process: proteolysis
Research Articles on CPA1
Similar Products
Product Notes
The CPA1 cpa1 (Catalog #AAA249644) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CPA1 / Carboxypeptidase An Antibody (aa301-350) IHC-plus reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CPA1 / Carboxypeptidase A can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA). ELISA (1:10000) IHC-P (10 ug/ml) WB (1:500 - 1:1000). Researchers should empirically determine the suitability of the CPA1 cpa1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CPA1 / Carboxypeptidase A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
