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Western Blot (WB) (All lanes : Anti-COX6C Antibody (C-term) at 1:8000 dilutionLane 1: human heart lysateLane 2: A-673 whole cell lysateLane 3: HepG2 whole cell lysateLane 4: U-2OS whole cell lysateLane 5: mouse heart lysateLane 6: rat kidney lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 9 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Rabbit COX6C Polyclonal Antibody | anti-COX6C antibody

COX6C Antibody (C-term)

Reactivity
Human, Mouse, Rat
Applications
Western Blot
Synonyms
COX6C; Polyclonal Antibody; COX6C Antibody (C-term); Purified Rabbit Polyclonal Antibody (Pab); Cytochrome c oxidase subunit 6C; Cytochrome c oxidase polypeptide Vic; anti-COX6C antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Ig
Specificity
This COX6C antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 41-75 amino acids from the C-terminal region of human COX6C.
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Length
75
Applicable Applications for anti-COX6C antibody
Western Blot (WB)
Application Notes
WB ~~ 1:8000
Antigen Source
Human
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(All lanes : Anti-COX6C Antibody (C-term) at 1:8000 dilutionLane 1: human heart lysateLane 2: A-673 whole cell lysateLane 3: HepG2 whole cell lysateLane 4: U-2OS whole cell lysateLane 5: mouse heart lysateLane 6: rat kidney lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 9 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (All lanes : Anti-COX6C Antibody (C-term) at 1:8000 dilutionLane 1: human heart lysateLane 2: A-673 whole cell lysateLane 3: HepG2 whole cell lysateLane 4: U-2OS whole cell lysateLane 5: mouse heart lysateLane 6: rat kidney lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 9 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-COX6C antibody
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Product Categories/Family for anti-COX6C antibody
References
Otsuka M.,et al.Nucleic Acids Res. 16:10916-10916(1988). Ohta S.,et al.Submitted (FEB-1996) to the EMBL/GenBank/DDBJ databases. Hofmann S.,et al.Cytogenet. Cell Genet. 83:226-227(1998). Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
8781
NCBI Official Full Name
cytochrome c oxidase subunit 6C
NCBI Official Synonym Full Names
cytochrome c oxidase subunit VIc
NCBI Official Symbol
COX6C
NCBI Protein Information
cytochrome c oxidase subunit 6C
UniProt Protein Name
Cytochrome c oxidase subunit 6C
Protein Family
UniProt Gene Name
COX6C
UniProt Entry Name
COX6C_HUMAN

NCBI Description

Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12. [provided by RefSeq, Jul 2010]

Uniprot Description

COX6C: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Belongs to the cytochrome c oxidase subunit 6c family.

Protein type: EC 1.9.3.1; Energy Metabolism - oxidative phosphorylation; Membrane protein, integral; Oxidoreductase; Mitochondrial

Chromosomal Location of Human Ortholog: 8q22.2

Cellular Component: mitochondrion; mitochondrial inner membrane; integral to membrane

Molecular Function: cytochrome-c oxidase activity

Biological Process: transcription initiation from RNA polymerase II promoter; cellular metabolic process; generation of precursor metabolites and energy; gene expression

Research Articles on COX6C

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Product Notes

The COX6C cox6c (Catalog #AAA9216646) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The COX6C Antibody (C-term) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's COX6C can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB ~~ 1:8000. Researchers should empirically determine the suitability of the COX6C cox6c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "COX6C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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