Testing Data
(Fig.1: Wells of a 96-microtiter plate were coated with different concentration of a mammalian expressed full-length SARS-CoV-2 Spike protein. The binding was detected by addition of 200 ng of biotinylated anti-Spike S polyclonal antibody per well. The reactivity was detected by HRP-conjugated Streptavidin.)
Rabbit COVID 19 Spike Coronavirus Polyclonal Antibody | anti-COVID-19 antibody
Coronavirus (COVID-19/Sars-Cov-2/2019nCov) Spike biotinylated Antibody
Applications
ELISA
Purity
Protein A Chromatography
Synonyms
COVID 19 Spike Coronavirus; Polyclonal Antibody; Coronavirus (COVID-19/Sars-Cov-2/2019nCov) Spike biotinylated Antibody; 2019 Novel Coronavirus; Coronavirus; CoV; COVID-19 virus; HCoV-2; Human Coronavirus 2019; SARS2; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Spike; anti-COVID-19 antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Protein A Chromatography
Form/Format
Purified. 25ug in PBS + 0.05% Azide
Sequence Positions
850-1050aa
Applicable Applications for anti-COVID-19 antibody
ELISA (EIA)
Immunogen
A partial length recombinant coronavirus Spike Protein (amino acids 850-1050) was used as the immunogen for this antibody.
Antigen
Coronavirus Spike Protein
Conjugate
Biotin
Preparation and Storage
Store at 4°C.
Testing Data
(Fig.1: Wells of a 96-microtiter plate were coated with different concentration of a mammalian expressed full-length SARS-CoV-2 Spike protein. The binding was detected by addition of 200 ng of biotinylated anti-Spike S polyclonal antibody per well. The reactivity was detected by HRP-conjugated Streptavidin.)
Testing Data
(Fig.1: Wells of a 96-microtiter plate were coated with different concentration of a mammalian expressed full-length SARS-CoV-2 Spike protein. The binding was detected by addition of 200 ng of biotinylated anti-Spike S polyclonal antibody per well. The reactivity was detected by HRP-conjugated Streptavidin.)
Related Product Information for anti-COVID-19 antibody
The spike (S) protein of nCoV/SARS-CoV-2/COVID-19 is one of the structural glycoproteins that remains embedded in viral envelope and acts as the fundamental component of early viral infection of nCoV/SARS-CoV-2/COVID-1 upon binding the host receptor. The nCoV/SARS-CoV-2/COVID-19 has a trimeric spike protein which has two main domains such as S1 domain for receptor binding and S2 domain for membrane fusion and several specific cleavage sites in S1- S2 boundary junction that needs a novel, endocytic protease- primed cleavage to get activated during infection. It mainly binds to the furin protein on the cell membrane which performs trypsin like proteolytic cleavage and then the protein gets activated facilitating its entry into the host. This transmembrane spike protein of nCoV/SARS-CoV-2/COVID-19 shares binding property to the Angiotensin Converting Enzyme 2 (ACE2) likely to that of SARS- CoV. The high affinity of nCoV/SARS-CoV-2/COVID-19 Spike protein for human ACE2 may contribute to the apparent ease with which nCoV/SARS-CoV-2/COVID-19 can spread from human-to-human and make nCoV/SARS-CoV-2/COVID-19 pandemic.
Product Categories/Family for anti-COVID-19 antibody
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Product Notes
The COVID-19 (Catalog #AAA669408) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 850-1050aa. AAA Biotech's COVID 19 Spike Coronavirus can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the COVID-19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "COVID 19 Spike Coronavirus, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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