Rabbit anti-Human CORO2A Polyclonal Antibody | anti-CORO2A antibody

CORO2A, ID (CORO2A, IR10, WDR2, Coronin-2A, WD repeat-containing protein 2) (APC)

Cat. Num. AAA6288000

• Gene Names: CORO2A; IR10; WDR2; CLIPINB
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: CORO2A; Polyclonal Antibody; ID (CORO2A; IR10; WDR2; Coronin-2A; WD repeat-containing protein 2) (APC); WD repeat-containing protein 2; anti-CORO2A antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
• Sequence Length: 525

• Applicable Applications for anti-CORO2A antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: CORO2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 184-213 amino acids from the Central region of human CORO2A.
• Conjugate: APC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(CORO2A Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the CORO2A antibody detected the CORO2A protein (arrow).)

Product Categories/Family for anti-CORO2A antibody

Antibodies; WD Repeat Proteins

References

Jin, Y., et al. Nat. Genet. 42(7):576-578(2010). Marshall, T.W., et al. J. Cell. Sci. 122 (PT 17), 3061-3069 (2009): Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005). Yoon, H.G., et al. Mol. Cell 12(3):723-734(2003). Yoon, H.G., et al. EMBO J. 22(6):1336-1346(2003).

NCBI and Uniprot Product Information

• NCBI GI #: 16554585
• NCBI GeneID: 7464
• NCBI Accession #: NP_438171.1; NP_003380.3
• NCBI GenBank Nucleotide #: NP_438171.1
• UniProt Accession #: Q92828
• NCBI Official Full Name: coronin-2A
• NCBI Official Synonym Full Names: coronin 2A
• NCBI Official Symbol: CORO2A
• NCBI Official Synonym Symbols: IR10; WDR2; CLIPINB
• NCBI Protein Information: coronin-2A
• UniProt Protein Name: Coronin-2A
• Protein Family: Coronin
• UniProt Gene Name: CORO2A
• UniProt Synonym Gene Names: IR10; WDR2

NCBI Description

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]