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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human cervical cancer using MBS768115 (CORO1C antibody) at dilution of 1:100)

Rabbit CORO1C Polyclonal Antibody | anti-CORO1C antibody

CORO1C Rabbit Polyclonal

Gene Names
CORO1C; HCRNN4
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
CORO1C; Polyclonal Antibody; CORO1C Rabbit Polyclonal; anti-CORO1C antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
474
Applicable Applications for anti-CORO1C antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
Immunogen
Coronin, actin binding protein, 1C
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human cervical cancer using MBS768115 (CORO1C antibody) at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human cervical cancer using MBS768115 (CORO1C antibody) at dilution of 1:100)

Testing Data

()

Testing Data ()

Western Blot (WB)

(mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with MBS768115 (CORO1C antibody) at dilution of 1:500)

Western Blot (WB) (mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with MBS768115 (CORO1C antibody) at dilution of 1:500)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
58,947 Da
NCBI Official Full Name
coronin-1C isoform b
NCBI Official Synonym Full Names
coronin 1C
NCBI Official Symbol
CORO1C
NCBI Official Synonym Symbols
HCRNN4
NCBI Protein Information
coronin-1C
UniProt Protein Name
Coronin-1C
Protein Family
UniProt Gene Name
CORO1C
UniProt Synonym Gene Names
CRN2; CRNN4
UniProt Entry Name
COR1C_HUMAN

NCBI Description

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]

Uniprot Description

coronin 1C: an ubiquitous, actin-binding cytoskeletal protein. May be involved in cytokinesis and motility. Belongs to the WD-repeat coronin family.

Protein type: Motility/polarity/chemotaxis; Actin-binding

Chromosomal Location of Human Ortholog: 12q24.1

Cellular Component: actin cytoskeleton; cytoplasm; flotillin complex; focal adhesion; lamellipodium; lateral plasma membrane; vesicle

Molecular Function: actin filament binding; protein binding; Rac GTPase binding

Biological Process: actin cytoskeleton organization and biogenesis; establishment of protein localization; negative regulation of focal adhesion formation; negative regulation of protein amino acid phosphorylation; neural crest cell migration; phagocytosis; regulation of focal adhesion formation; regulation of protein amino acid phosphorylation; signal transduction

Research Articles on CORO1C

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Product Notes

The CORO1C coro1c (Catalog #AAA768115) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CORO1C Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CORO1C can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the CORO1C coro1c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CORO1C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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