Western Blot (WB)
(Western blot analysis of hGJA7-H104.Connexin in MDA-MB435 cell line lysates (35ug/lane).GJA7 (arrow) was detected using the purified Pab.)
Rabbit anti-Human Connexin 45 Polyclonal Antibody | anti-Cx45 antibody
Connexin 45, NT (Gap Junction gamma-1 Protein, Gap Junction alpha-7 Protein, GJA7, Connexin-45, Cx45, GJC1) (PE)
FLISA: 1:1,000
WB: 1:100-1:500
Applications are based on unconjugated antibody.
Western Blot (WB)
(Western blot analysis of hGJA7-H104.Connexin in MDA-MB435 cell line lysates (35ug/lane).GJA7 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of hGJA7-H104.Connexin in MDA-MB435 cell line lysates (35ug/lane).GJA7 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008]
Uniprot Description
GJC1: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Gamma-type subfamily.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Cell adhesion
Chromosomal Location of Human Ortholog: 17q21.31
Cellular Component: connexon complex; endoplasmic reticulum membrane; plasma membrane; gap junction; integral to membrane
Molecular Function: ion channel activity; gap junction channel activity
Biological Process: cardiac muscle development; synaptic transmission; intercellular junction assembly; visual perception; muscle contraction; gap junction assembly; transport; vasculogenesis; cell development
Research Articles on Cx45
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Product Notes
The Cx45 gjc1 (Catalog #AAA6470199) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Connexin 45, NT (Gap Junction gamma-1 Protein, Gap Junction alpha-7 Protein, GJA7, Connexin-45, Cx45, GJC1) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Connexin 45 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, FLISA, Western Blot (WB). IHC-P: 1:50-1:100 FLISA: 1:1,000 WB: 1:100-1:500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the Cx45 gjc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Connexin 45, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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